Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50021645
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643046(CHEMBL5593400)
Affinity DataKi:  5.60nMAssay Description:Competitive type of inhibition at human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643045(CHEMBL5568952)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643044(CHEMBL5574138)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643043(CHEMBL5573291)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643040(CHEMBL5569484)
Affinity DataKi:  17nMAssay Description:Mixed type of inhibition at human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643051(CHEMBL5567105)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643042(CHEMBL5573951)
Affinity DataKi:  35nMAssay Description:Mixed type of inhibition at human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643046(CHEMBL5593400)
Affinity DataIC50: 38nMAssay Description:Inhibition of human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643053(CHEMBL5567018)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643049(CHEMBL5565903)
Affinity DataKi:  46nMAssay Description:Mixed type of inhibition at human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643039(CHEMBL5574747)
Affinity DataIC50: 59nMAssay Description:Inhibition of human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643054(CHEMBL5569141)
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643047(CHEMBL5575498)
Affinity DataIC50: 66nMAssay Description:Inhibition of human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643041(CHEMBL5572109)
Affinity DataIC50: 68nMAssay Description:Inhibition of human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643040(CHEMBL5569484)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643048(CHEMBL5569676)
Affinity DataKi:  79nMAssay Description:Mixed type of inhibition at human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643049(CHEMBL5565903)
Affinity DataIC50: 126nMAssay Description:Inhibition of human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643042(CHEMBL5573951)
Affinity DataIC50: 172nMAssay Description:Inhibition of human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643055(CHEMBL5572084)
Affinity DataIC50: 177nMAssay Description:Inhibition of human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643050(CHEMBL5572424)
Affinity DataIC50: 178nMAssay Description:Inhibition of human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643052(CHEMBL4095302)
Affinity DataIC50: 189nMAssay Description:Inhibition of human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCocaine esterase(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50643048(CHEMBL5569676)
Affinity DataIC50: 193nMAssay Description:Inhibition of human recombinant CES2 activity assessed as fluorescence of the AP product using Benz-AP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed