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Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50022389
TargetNEDD8-activating enzyme E1 regulatory subunit(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50285607(MLN-4924 | MLN-4924003 | Pevonedistat)
Affinity DataIC50: 4nMAssay Description:Inhibition of NAE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetNEDD8-activating enzyme E1 regulatory subunit(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651690(CHEMBL5633567)
Affinity DataIC50: 4nMAssay Description:Inhibition of NAE (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50525354(CHEMBL4517307 | US12012467, Compound DI-591)
Affinity DataKi:  12nMAssay Description:Inhibition of DCN1 (unknown origin) assessed as inhibition constant incubated for 30 min by competitive FP binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50525343(CHEMBL4440896 | US11116757, No. A29)
Affinity DataIC50: 40nMAssay Description:Inhibition of DCN1 (unknown origin) incubated for 30 mins by competitive FP binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDCN1-like protein 1(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50460801(CHEMBL4086524 | US11116757, No. Table11.10)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of DCN1 (unknown origin) incubated for 30 mins by competitive FP binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetNEDD8-activating enzyme E1 regulatory subunit(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50651689(CHEMBL5632724)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of NAE (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed