Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50021656
TargetEpidermal growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human EGFR L858R/T790M mutant (695 to 10121 residues) expressed in Sf9 cells by ELISA methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50632920(CHEMBL5404639)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50594717(CHEMBL5173070)
Affinity DataIC50: 18nMAssay Description:Inhibition of FGFR1 (unknown origin) incubated for 1 hr in presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50643128(CHEMBL5570405)
Affinity DataIC50: 23nMAssay Description:Inhibition of human EGFR L858R/T790M mutant (695 to 10121 residues) expressed in Sf9 cells by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50594717(CHEMBL5173070)
Affinity DataIC50: 43nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin) incubated for 1 hr in presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetActivated CDC42 kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50084464(CHEMBL3426891)
Affinity DataIC50: 58nMAssay Description:Inhibition of ACK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetActivated CDC42 kinase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50643128(CHEMBL5570405)
Affinity DataIC50: 263nMAssay Description:Inhibition of ACK1 (unknown origin) by ELISA methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50594717(CHEMBL5173070)
Affinity DataIC50: 1.14E+3nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 1 hr in presence of ATP by caliper mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50632920(CHEMBL5404639)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed