Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50019607
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 6760BDBM6760(CHEMBL281948 | methyl (15S,16R,18R)-16-hydroxy-15-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of N-terminal HA-tagged recombinant wild-type human MLK3 overexpressed in HEK293A cells preincubated for 10 mins followed by [gamma-32P]AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620990BDBM50620990(CHEMBL5403058)
Affinity DataIC50: 6nMAssay Description:Inhibition of human MLK3 by ATP-competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620994BDBM50620994(CHEMBL5397520)
Affinity DataIC50: 6nMAssay Description:Inhibition of human MLK3 by ATP-competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620999BDBM50620999(CHEMBL5417152)
Affinity DataIC50: 8nMAssay Description:Inhibition of human MLK3 by ATP-competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621000BDBM50621000(CHEMBL5436267)
Affinity DataIC50: 11nMAssay Description:Inhibition of human MLK3 by ATP-competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621002BDBM50621002(CHEMBL5409050)
Affinity DataIC50: 14nMAssay Description:Inhibition of human MLK3 by ATP-competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621000BDBM50621000(CHEMBL5436267)
Affinity DataIC50: 14nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621004BDBM50621004(CHEMBL5416972)
Affinity DataIC50: 14nMAssay Description:Inhibition of human MLK3 by ATP-competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620995BDBM50620995(CHEMBL5397819)
Affinity DataIC50: 14nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620997BDBM50620997(CHEMBL5436833)
Affinity DataIC50: 15nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620999BDBM50620999(CHEMBL5417152)
Affinity DataIC50: 16nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621003BDBM50621003(CHEMBL5435826)
Affinity DataIC50: 17nMAssay Description:Inhibition of human MLK3 by ATP-competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620995BDBM50620995(CHEMBL5397819)
Affinity DataIC50: 20nMAssay Description:Inhibition of human MLK3 by ATP-competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621003BDBM50621003(CHEMBL5435826)
Affinity DataIC50: 22nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621004BDBM50621004(CHEMBL5416972)
Affinity DataIC50: 22nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24942BDBM24942(methyl (15S,16R,18R)-10,23-bis[(ethylsulfanyl)meth...)
Affinity DataIC50: 23nMAssay Description:Inhibition of N-terminal GST-tagged recombinant MLK3 (unknown origin) expressed in insect cells incubated for 15 mins in presence of [gamma-32P]ATP b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621001BDBM50621001(CHEMBL5440213)
Affinity DataIC50: 24nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620705BDBM50620705(CHEMBL5413518)
Affinity DataIC50: 24nMAssay Description:Inhibition of MLK3 (unknown origin) by cell-free radiolabeled ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620996BDBM50620996(CHEMBL5421283)
Affinity DataIC50: 25nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620996BDBM50620996(CHEMBL5421283)
Affinity DataIC50: 25nMAssay Description:Inhibition of human MLK3 by ATP-competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620997BDBM50620997(CHEMBL5436833)
Affinity DataIC50: 26nMAssay Description:Inhibition of human MLK3 by ATP-competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621001BDBM50621001(CHEMBL5440213)
Affinity DataIC50: 27nMAssay Description:Inhibition of human MLK3 by ATP-competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621002BDBM50621002(CHEMBL5409050)
Affinity DataIC50: 34nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620990BDBM50620990(CHEMBL5403058)
Affinity DataIC50: 34nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620994BDBM50620994(CHEMBL5397520)
Affinity DataIC50: 47nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620993BDBM50620993(CHEMBL5410283)
Affinity DataIC50: 57nMAssay Description:Inhibition of human MLK3 by ATP-competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620998BDBM50620998(CHEMBL5407648)
Affinity DataIC50: 63nMAssay Description:Inhibition of human MLK3 by ATP-competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620998BDBM50620998(CHEMBL5407648)
Affinity DataIC50: 64nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620992BDBM50620992(CHEMBL5408099)
Affinity DataIC50: 84nMAssay Description:Inhibition of human MLK3 by ATP-competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620992BDBM50620992(CHEMBL5408099)
Affinity DataIC50: 136nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50506912BDBM50506912(CHEMBL235641)
Affinity DataIC50: 144nMAssay Description:Inhibition of human MLK3 by ATP-competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 11(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620991BDBM50620991(CHEMBL5401171)
Affinity DataIC50: 4.66E+3nMAssay Description:Inhibition of human MLK3 by ATP-competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 9(Human)
Chungnam National University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50620991BDBM50620991(CHEMBL5401171)
Affinity DataIC50: 5.92E+3nMAssay Description:Inhibition of MLK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed