Compile Data Set for Download or QSAR
Report error Found 84 Enz. Inhib. hit(s) with all data for entry = 50021009
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636011BDBM50636011(CHEMBL5560228)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636007BDBM50636007(CHEMBL5557809)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636009BDBM50636009(CHEMBL5558965)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636010BDBM50636010(CHEMBL5560445)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636014BDBM50636014(CHEMBL5561221)
Affinity DataIC50: 3nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636019BDBM50636019(CHEMBL5542831)
Affinity DataIC50: 3nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636018BDBM50636018(CHEMBL5556918)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636008BDBM50636008(CHEMBL5560869)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635995BDBM50635995(CHEMBL5558185)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635990BDBM50635990(CHEMBL5555917)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635995BDBM50635995(CHEMBL5558185)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of GLK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635990BDBM50635990(CHEMBL5555917)
Affinity DataIC50: 10nMAssay Description:Inhibition of GLK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635997BDBM50635997(CHEMBL5555788)
Affinity DataIC50: 12nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-2(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636011BDBM50636011(CHEMBL5560228)
Affinity DataEC50:  12nMAssay Description:Activation of IL-2 in human Jurkat cells incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635995BDBM50635995(CHEMBL5558185)
Affinity DataIC50: 12nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636013BDBM50636013(CHEMBL5561074)
Affinity DataIC50: 13nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635990BDBM50635990(CHEMBL5555917)
Affinity DataIC50: 13nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635999BDBM50635999(CHEMBL5555659)
Affinity DataIC50: 13nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635997BDBM50635997(CHEMBL5555788)
Affinity DataIC50: 15nMAssay Description:Inhibition of GLK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636017BDBM50636017(CHEMBL5566879)
Affinity DataIC50: 17nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635999BDBM50635999(CHEMBL5555659)
Affinity DataIC50: 18nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636021BDBM50636021(CHEMBL5557081)
Affinity DataIC50: 19nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636003BDBM50636003(CHEMBL5558967)
Affinity DataIC50: 20nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635999BDBM50635999(CHEMBL5555659)
Affinity DataIC50: 22nMAssay Description:Inhibition of GLK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635997BDBM50635997(CHEMBL5555788)
Affinity DataIC50: 22nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636022BDBM50636022(CHEMBL5556436)
Affinity DataIC50: 25nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636016BDBM50636016(CHEMBL5523660)
Affinity DataIC50: 28nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636003BDBM50636003(CHEMBL5558967)
Affinity DataIC50: 28nMAssay Description:Inhibition of LCK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 3(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636003BDBM50636003(CHEMBL5558967)
Affinity DataIC50: 30nMAssay Description:Inhibition of GLK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636015BDBM50636015(CHEMBL5557243)
Affinity DataIC50: 34nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-2(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636012BDBM50636012(CHEMBL5557745)
Affinity DataEC50:  45nMAssay Description:Activation of IL-2 in human Jurkat cells incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636001BDBM50636001(CHEMBL5532543)
Affinity DataIC50: 52nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-2(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636016BDBM50636016(CHEMBL5523660)
Affinity DataEC50:  73nMAssay Description:Activation of IL-2 in human Jurkat cells incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636000BDBM50636000(CHEMBL5562369)
Affinity DataIC50: 83nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-2(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636009BDBM50636009(CHEMBL5558965)
Affinity DataEC50:  90nMAssay Description:Activation of IL-2 in human Jurkat cells incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636012BDBM50636012(CHEMBL5557745)
Affinity DataIC50: 96nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-2(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636015BDBM50636015(CHEMBL5557243)
Affinity DataEC50:  97nMAssay Description:Activation of IL-2 in human Jurkat cells incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-2(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50636014BDBM50636014(CHEMBL5561221)
Affinity DataEC50:  108nMAssay Description:Activation of IL-2 in human Jurkat cells incubated for 24 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635979BDBM50635979(CHEMBL5549998)
Affinity DataIC50: 120nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635974BDBM50635974(CHEMBL5561800)
Affinity DataIC50: 125nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635970BDBM50635970(CHEMBL5542339)
Affinity DataIC50: 134nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635983BDBM50635983(CHEMBL5560271)
Affinity DataIC50: 141nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635998BDBM50635998(CHEMBL5567659)
Affinity DataIC50: 142nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635978BDBM50635978(CHEMBL5532107)
Affinity DataIC50: 149nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635987BDBM50635987(CHEMBL5564933)
Affinity DataIC50: 160nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635989BDBM50635989(CHEMBL5557064)
Affinity DataIC50: 162nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635973BDBM50635973(CHEMBL5558031)
Affinity DataIC50: 166nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635991BDBM50635991(CHEMBL5559928)
Affinity DataIC50: 187nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635993BDBM50635993(CHEMBL5556160)
Affinity DataIC50: 207nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50635972BDBM50635972(CHEMBL5567723)
Affinity DataIC50: 228nMAssay Description:Inhibition of HPK1 (unknown origin) preincubated for 10 mins followed by ATP addition measured after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
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