Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50021933
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50646265(CHEMBL5592797)
Affinity DataIC50: 49nMAssay Description:Inhibition of GGDPS (unknown origin) using uRAP1a as substrate in RPMI-8226 cells assessed as disruption of geranylgeranylation by measuring unmodifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50646264(CHEMBL5591404)
Affinity DataIC50: 52nMAssay Description:Inhibition of GGDPS (unknown origin) using uRAP1a as substrate in RPMI-8226 cells assessed as disruption of geranylgeranylation by measuring unmodifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50646263(CHEMBL5591107)
Affinity DataIC50: 270nMAssay Description:Inhibition of GGDPS (unknown origin) using uRAP1a as substrate in RPMI-8226 cells assessed as disruption of geranylgeranylation by measuring unmodifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50646262(CHEMBL5595294)
Affinity DataIC50: 3.76E+3nMAssay Description:Inhibition of GGDPS (unknown origin) using uRAP1a as substrate in RPMI-8226 cells assessed as disruption of geranylgeranylation by measuring unmodifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50646266(CHEMBL5590769)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of GGDPS (unknown origin) using uRAP1a as substrate in RPMI-8226 cells assessed as disruption of geranylgeranylation by measuring unmodifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed