Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50021027
TargetProstaglandin G/H synthase 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 710nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50636121(CHEMBL5565293)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of human recombinant COX-2 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Sheep)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM13066({2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid |...)
Affinity DataIC50: 6.41E+3nMAssay Description:Inhibition of sheep COX-1 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Sheep)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50636121(CHEMBL5565293)
Affinity DataIC50: 2.63E+4nMAssay Description:Inhibition of sheep COX-1 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mins by fluor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of sheep COX-1 using arachidonic acid as substrate pretreated for 5 mins followed by substrate addition and measured after 2 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed