Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50021764
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644678(CHEMBL5568649)
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal His-tagged human Cbl-b (40 to 426 residues) expressed in Escherichia coli by measured for 90 mins by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM711128(2-(3-((1r,3r)-3-methoxy-1-(4-methyl-4H- 1,2,4-tria...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Cbl-b (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM711128(2-(3-((1r,3r)-3-methoxy-1-(4-methyl-4H- 1,2,4-tria...)
Affinity DataKd:  4nMAssay Description:Binding affinity to CBl-b (unknown origin) assessed as dissociation constant by Surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644679(CHEMBL5568870)
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal His-tagged human Cbl-b (40 to 426 residues) expressed in Escherichia coli by measured for 90 mins by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50634588(CHEMBL5421689)
Affinity DataIC50: 5nMAssay Description:Inhibition of Cbl-b (unknown origin) ubiquitination by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50634588(CHEMBL5421689)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant Cbl-b (unknown origin) ubiquitination incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644678(CHEMBL5568649)
Affinity DataIC50: 5nMAssay Description:Inhibition of Cbl-b (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644670(CHEMBL5593645)
Affinity DataIC50: 7nMAssay Description:Inhibition of Cbl-b (unknown origin) ubiquitination by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644670(CHEMBL5593645)
Affinity DataIC50: 7nMAssay Description:Inhibition of Cbl-b (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50634588(CHEMBL5421689)
Affinity DataKd:  8nMAssay Description:Binding affinity to CBl-b (unknown origin) assessed as dissociation constant by Surface plasmon resonanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase CBL-C(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644670(CHEMBL5593645)
Affinity DataIC50: 8nMAssay Description:Inhibition of c-Cbl (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644677(CHEMBL5567617)
Affinity DataIC50: 10nMAssay Description:Inhibition of Cbl-b (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-C(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644678(CHEMBL5568649)
Affinity DataIC50: 10nMAssay Description:Inhibition of c-Cbl (unknown origin) expressed in Escherichia coli measured for 90 mins by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644677(CHEMBL5567617)
Affinity DataIC50: 13nMAssay Description:Inhibition of N-terminal His-tagged human Cbl-b (40 to 426 residues) expressed in Escherichia coli by measured for 90 mins by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM585844(US11530229, Compound 60)
Affinity DataKd:  20nMAssay Description:Binding affinity to CBl-b (unknown origin) assessed as dissociation constant by Surface plasmon resonanceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM585844(US11530229, Compound 60)
Affinity DataIC50: 20nMAssay Description:Inhibition of Cbl-b (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644672(CHEMBL5572988)
Affinity DataIC50: 20nMAssay Description:Inhibition of Cbl-b (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644672(CHEMBL5572988)
Affinity DataIC50: 20nMAssay Description:Inhibition of Cbl-b (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644676(CHEMBL5571885)
Affinity DataIC50: 20nMAssay Description:Inhibition of Cbl-b (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM585844(US11530229, Compound 60)
Affinity DataIC50: 21nMAssay Description:Inhibition of Cbl-b (unknown origin) ubiquitination by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644676(CHEMBL5571885)
Affinity DataIC50: 25nMAssay Description:Inhibition of N-terminal His-tagged human Cbl-b (40 to 426 residues) expressed in Escherichia coli by measured for 90 mins by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-C(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642865(CHEMBL5565433)
Affinity DataIC50: 30nMAssay Description:Inhibition of c-Cbl (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642865(CHEMBL5565433)
Affinity DataIC50: 30nMAssay Description:Inhibition of biotinylated recombinant Cbl-b (36 to 427 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) measured for 1 hr by TR-FRE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase CBL-C(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644679(CHEMBL5568870)
Affinity DataIC50: 40nMAssay Description:Inhibition of c-Cbl (unknown origin) expressed in Escherichia coli measured for 90 mins by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644669(CHEMBL5570145)
Affinity DataIC50: 100nMAssay Description:Inhibition of biotinylated recombinant Cbl-b (36 to 427 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) measured for 1 hr by TR-FRE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644675(CHEMBL5565236)
Affinity DataIC50: 100nMAssay Description:Inhibition of biotinylated recombinant Cbl-b (36 to 427 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) measured for 1 hr by TR-FRE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644673(CHEMBL5563171)
Affinity DataIC50: 100nMAssay Description:Inhibition of Cbl-b (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644669(CHEMBL5570145)
Affinity DataIC50: 100nMAssay Description:Inhibition of Cbl-b (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644675(CHEMBL5565236)
Affinity DataIC50: 100nMAssay Description:Inhibition of Cbl-b (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644669(CHEMBL5570145)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant Cbl-b (unknown origin) ubiquitination incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644673(CHEMBL5563171)
Affinity DataIC50: 100nMAssay Description:Inhibition of biotinylated recombinant Cbl-b (36 to 427 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) measured for 1 hr by TR-FRE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644674(CHEMBL5569013)
Affinity DataIC50: 200nMAssay Description:Inhibition of biotinylated recombinant Cbl-b (36 to 427 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) measured for 1 hr by TR-FRE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644674(CHEMBL5569013)
Affinity DataIC50: 200nMAssay Description:Inhibition of Cbl-b (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644671(CHEMBL5565675)
Affinity DataIC50: 200nMAssay Description:Inhibition of Cbl-b (unknown origin) by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644671(CHEMBL5565675)
Affinity DataIC50: 200nMAssay Description:Inhibition of Cbl-b (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-C(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644671(CHEMBL5565675)
Affinity DataIC50: 200nMAssay Description:Inhibition of c-Cbl (unknown origin) by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-C(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM711128(2-(3-((1r,3r)-3-methoxy-1-(4-methyl-4H- 1,2,4-tria...)
Affinity DataKd:  210nMAssay Description:Binding affinity to c-Cbl (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644681(CHEMBL5593044)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of Cbl-b (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-C(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644674(CHEMBL5569013)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of c-Cbl (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644680(CHEMBL5591512)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Cbl-b (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644679(CHEMBL5568870)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Cbl-b (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642748(CHEMBL5564717)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant Cbl-b by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642748(CHEMBL5564717)
Affinity DataKd:  1.60E+4nMAssay Description:Binding affinity to human recombinant Cbl-b assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642747(CHEMBL5583756)
Affinity DataKd:  2.80E+4nMAssay Description:Binding affinity to CBl-b (unknown origin) assessed as dissociation constant by Surface plasmon resonanceMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50642747(CHEMBL5583756)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of Cbl-b (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase CBL-B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50644668(CHEMBL5572015)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant Cbl-b (unknown origin) ubiquitination incubated for 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed