Compile Data Set for Download or QSAR
Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50022314
TargetActivin receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650702(CHEMBL5630864)
Affinity DataIC50: 2nMAssay Description:Inhibition of N-terminal GST-his6 tagged human recombinant ALK2 (145 to 509 residues) expressed in Sf9 insect cells in presence of ATP by ADP-glo ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650705(CHEMBL5631116)
Affinity DataIC50: 2nMAssay Description:Inhibition of N-terminal GST-his6 tagged human recombinant ALK2 (145 to 509 residues) expressed in Sf9 insect cells in presence of ATP by ADP-glo ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650704(CHEMBL5630109)
Affinity DataIC50: 2nMAssay Description:Inhibition of N-terminal GST-his6 tagged human recombinant ALK2 (145 to 509 residues) expressed in Sf9 insect cells in presence of ATP by ADP-glo ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650706(CHEMBL5630485)
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal GST-his6 tagged human recombinant ALK2 (145 to 509 residues) expressed in Sf9 insect cells in presence of ATP by ADP-glo ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650703(CHEMBL5630025)
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal GST-his6 tagged human recombinant ALK2 (145 to 509 residues) expressed in Sf9 insect cells in presence of ATP by ADP-glo ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650702(CHEMBL5630864)
Affinity DataIC50: 5nMAssay Description:Inhibition of ALK2 in human HEK293 cells using NanoGlo as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650704(CHEMBL5630109)
Affinity DataIC50: 6nMAssay Description:Inhibition of ALK2 in human HEK293 cells using NanoGlo as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650703(CHEMBL5630025)
Affinity DataIC50: 7nMAssay Description:Inhibition of ALK2 in human HEK293 cells using NanoGlo as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650707(CHEMBL5630942)
Affinity DataIC50: 7nMAssay Description:Inhibition of N-terminal GST-his6 tagged human recombinant ALK2 (145 to 509 residues) expressed in Sf9 insect cells in presence of ATP by ADP-glo ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650706(CHEMBL5630485)
Affinity DataIC50: 11nMAssay Description:Inhibition of ALK2 in human HEK293 cells using NanoGlo as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650701(CHEMBL5630245)
Affinity DataIC50: 13nMAssay Description:Inhibition of N-terminal GST-his6 tagged human recombinant ALK2 (145 to 509 residues) expressed in Sf9 insect cells in presence of ATP by ADP-glo ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650705(CHEMBL5631116)
Affinity DataIC50: 15nMAssay Description:Inhibition of ALK2 in human HEK293 cells using NanoGlo as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650707(CHEMBL5630942)
Affinity DataIC50: 18nMAssay Description:Inhibition of ALK2 in human HEK293 cells using NanoGlo as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50528194(CHEMBL4517408)
Affinity DataIC50: 26nMAssay Description:Inhibition of ALK2 in human HEK293 cells using NanoGlo as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650701(CHEMBL5630245)
Affinity DataIC50: 45nMAssay Description:Inhibition of ALK2 in human HEK293 cells using NanoGlo as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650702(CHEMBL5630864)
Affinity DataIC50: 104nMAssay Description:Inhibition of N-terminal GST-his6 tagged human recombinant ALK5 (200 to 503 residues) expressed in Sf9 insect cells in presence of ATP by ADP-glo ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650703(CHEMBL5630025)
Affinity DataIC50: 187nMAssay Description:Inhibition of N-terminal GST-his6 tagged human recombinant ALK5 (200 to 503 residues) expressed in Sf9 insect cells in presence of ATP by ADP-glo ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650704(CHEMBL5630109)
Affinity DataIC50: 224nMAssay Description:Inhibition of N-terminal GST-his6 tagged human recombinant ALK5 (200 to 503 residues) expressed in Sf9 insect cells in presence of ATP by ADP-glo ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650702(CHEMBL5630864)
Affinity DataIC50: 224nMAssay Description:Inhibition of ALK5 (unknown origin) transfected in human HEK293 cells cotransfected with CAGA reporter encoding luciferase by Dual luciferase reporte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650703(CHEMBL5630025)
Affinity DataIC50: 347nMAssay Description:Inhibition of ALK5 (unknown origin) transfected in human HEK293 cells cotransfected with CAGA reporter encoding luciferase by Dual luciferase reporte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650705(CHEMBL5631116)
Affinity DataIC50: 350nMAssay Description:Inhibition of N-terminal GST-his6 tagged human recombinant ALK5 (200 to 503 residues) expressed in Sf9 insect cells in presence of ATP by ADP-glo ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650704(CHEMBL5630109)
Affinity DataIC50: 471nMAssay Description:Inhibition of ALK5 (unknown origin) transfected in human HEK293 cells cotransfected with CAGA reporter encoding luciferase by Dual luciferase reporte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650700(CHEMBL5624556)
Affinity DataIC50: 609nMAssay Description:Inhibition of N-terminal GST-his6 tagged human recombinant ALK2 (145 to 509 residues) expressed in Sf9 insect cells in presence of ATP by ADP-glo ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivin receptor type-1B(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50528194(CHEMBL4517408)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of human ALK4 (150 to end residues) incubated for 40 mins in presence of ATP by scintillation based radiometric LeadHunter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650705(CHEMBL5631116)
Affinity DataIC50: 1.19E+3nMAssay Description:Inhibition of ALK5 (unknown origin) transfected in human HEK293 cells cotransfected with CAGA reporter encoding luciferase by Dual luciferase reporte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650701(CHEMBL5630245)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of N-terminal GST-his6 tagged human recombinant ALK5 (200 to 503 residues) expressed in Sf9 insect cells in presence of ATP by ADP-glo ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650706(CHEMBL5630485)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of ALK5 (unknown origin) transfected in human HEK293 cells cotransfected with CAGA reporter encoding luciferase by Dual luciferase reporte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650701(CHEMBL5630245)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of ALK5 (unknown origin) transfected in human HEK293 cells cotransfected with CAGA reporter encoding luciferase by Dual luciferase reporte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650706(CHEMBL5630485)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of N-terminal GST-his6 tagged human recombinant ALK5 (200 to 503 residues) expressed in Sf9 insect cells in presence of ATP by ADP-glo ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50528194(CHEMBL4517408)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of ALK5 (unknown origin) transfected in human HEK293 cells cotransfected with CAGA reporter encoding luciferase by Dual luciferase reporte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650707(CHEMBL5630942)
Affinity DataIC50: 3.92E+3nMAssay Description:Inhibition of N-terminal GST-his6 tagged human recombinant ALK5 (200 to 503 residues) expressed in Sf9 insect cells in presence of ATP by ADP-glo ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650707(CHEMBL5630942)
Affinity DataIC50: 3.96E+3nMAssay Description:Inhibition of ALK5 (unknown origin) transfected in human HEK293 cells cotransfected with CAGA reporter encoding luciferase by Dual luciferase reporte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650700(CHEMBL5624556)
Affinity DataIC50: 7.69E+3nMAssay Description:Inhibition of ALK5 (unknown origin) transfected in human HEK293 cells cotransfected with CAGA reporter encoding luciferase by Dual luciferase reporte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Ontario Institute for Cancer Research

Curated by ChEMBL
LigandPNGBDBM50650700(CHEMBL5624556)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ALK2 in human HEK293 cells using NanoGlo as substrate incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed