Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50020904
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634732(CHEMBL5558316)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in baculovirus infected Sf9 insect cells incubated for 60 mins in presence of ATP by microp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634721(CHEMBL5517819)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in baculovirus infected Sf9 insect cells incubated for 60 mins in presence of ATP by microp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50184872(4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]-pyridin-2-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of ALK5 (unknown origin) kinase domain by biochemical binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50012803(CHEMBL3261090)
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in baculovirus infected Sf9 insect cells incubated for 60 mins in presence of ATP by microp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634723(CHEMBL5512434)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in baculovirus infected Sf9 insect cells incubated for 60 mins in presence of ATP by microp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634731(CHEMBL5517775)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in baculovirus infected Sf9 insect cells incubated for 60 mins in presence of ATP by microp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634726(CHEMBL5558398)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in baculovirus infected Sf9 insect cells incubated for 60 mins in presence of ATP by microp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634718(CHEMBL5556410)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in baculovirus infected Sf9 insect cells incubated for 60 mins in presence of ATP by microp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634719(CHEMBL5549953)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in baculovirus infected Sf9 insect cells incubated for 60 mins in presence of ATP by microp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50298220(2-(5-(benzo[d][1,3]dioxol-5-yl)-2-tert-butyl-1H-im...)
Affinity DataIC50: 47nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634725(CHEMBL5517800)
Affinity DataIC50: 61nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in baculovirus infected Sf9 insect cells incubated for 60 mins in presence of ATP by microp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634730(CHEMBL5557513)
Affinity DataIC50: 66nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in baculovirus infected Sf9 insect cells incubated for 60 mins in presence of ATP by microp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634716(CHEMBL5517762)
Affinity DataIC50: 73nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in baculovirus infected Sf9 insect cells incubated for 60 mins in presence of ATP by microp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634722(CHEMBL5557604)
Affinity DataIC50: 84nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in baculovirus infected Sf9 insect cells incubated for 60 mins in presence of ATP by microp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634724(CHEMBL5558039)
Affinity DataIC50: 87nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in baculovirus infected Sf9 insect cells incubated for 60 mins in presence of ATP by microp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634720(CHEMBL5555953)
Affinity DataIC50: 92nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in baculovirus infected Sf9 insect cells incubated for 60 mins in presence of ATP by microp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50110208(SB-431542 | cid_4521392 | 4-(5-(benzo[d][1,3]dioxo...)
Affinity DataIC50: 94nMAssay Description:Inhibition of N-terminal GST-tagged ALK5 (unknown origin) expressed in baculovirus expression system using GST-tagged Smad3 as substrate assessed as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50015640(LY-2157299 | GALUNISERTIB)
Affinity DataIC50: 119nMAssay Description:Inhibition of ALK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50015640(LY-2157299 | GALUNISERTIB)
Affinity DataIC50: 129nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in baculovirus infected Sf9 insect cells incubated for 60 mins in presence of ATP by microp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634715(CHEMBL5532435)
Affinity DataIC50: 317nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in baculovirus infected Sf9 insect cells incubated for 60 mins in presence of ATP by microp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634717(CHEMBL5517679)
Affinity DataIC50: 377nMAssay Description:Inhibition of human recombinant GST-tagged ALK5 expressed in baculovirus infected Sf9 insect cells incubated for 60 mins in presence of ATP by microp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634721(CHEMBL5517819)
Affinity DataIC50: 435nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50015640(LY-2157299 | GALUNISERTIB)
Affinity DataIC50: 493nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634719(CHEMBL5549953)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634725(CHEMBL5517800)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634724(CHEMBL5558039)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634723(CHEMBL5512434)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634732(CHEMBL5558316)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634731(CHEMBL5517775)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50012803(CHEMBL3261090)
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634720(CHEMBL5555953)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634718(CHEMBL5556410)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634722(CHEMBL5557604)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634729(CHEMBL5557444)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634728(CHEMBL5558988)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634727(CHEMBL5555369)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634726(CHEMBL5558398)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634717(CHEMBL5517679)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634716(CHEMBL5517762)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634715(CHEMBL5532435)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50634730(CHEMBL5557513)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant p38alpha expressed in Escherichia coli incubated for 60 mins in presence of ATP by microplate scintillation counterMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed