Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50021705
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643750(CHEMBL5575150)
Affinity DataIC50: 0.400nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643748(CHEMBL5574671)
Affinity DataIC50: 0.700nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643763(CHEMBL5594712)
Affinity DataIC50: 0.700nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643768(CHEMBL5589825)
Affinity DataIC50: 1.90nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643749(CHEMBL5566312)
Affinity DataIC50: 2.30nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643762(CHEMBL5591151)
Affinity DataIC50: 2.40nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643770(CHEMBL5573122)
Affinity DataIC50: 2.5nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643744(CHEMBL4303573)
Affinity DataIC50: 2.70nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643780(CHEMBL5590478)
Affinity DataIC50: 3.80nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643758(CHEMBL5593424)
Affinity DataIC50: 5nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643760(CHEMBL5572905)
Affinity DataIC50: 5.30nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643759(CHEMBL5572011)
Affinity DataIC50: 6nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643769(CHEMBL5567438)
Affinity DataIC50: 6.80nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643784(CHEMBL5565290)
Affinity DataIC50: 8.10nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643766(CHEMBL5573131)
Affinity DataIC50: 8.5nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643778(CHEMBL5571595)
Affinity DataIC50: 9.40nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643771(Evetifator | DNL-343)
Affinity DataIC50: 9.80nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643783(CHEMBL5569682)
Affinity DataIC50: 12nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643767(CHEMBL5595443)
Affinity DataIC50: 12nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643772(CHEMBL5564968)
Affinity DataIC50: 15nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643765(CHEMBL5592433)
Affinity DataIC50: 19nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643752(CHEMBL5565662)
Affinity DataIC50: 34nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643757(CHEMBL5575064)
Affinity DataIC50: 40nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643776(CHEMBL5574460)
Affinity DataIC50: 52nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643782(CHEMBL5570121)
Affinity DataIC50: 58nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643773(CHEMBL5594694)
Affinity DataIC50: 61nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643781(CHEMBL5575386)
Affinity DataIC50: 68nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643779(CHEMBL5563612)
Affinity DataIC50: 103nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643751(CHEMBL5570649)
Affinity DataIC50: 106nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643764(CHEMBL5569542)
Affinity DataIC50: 111nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643761(CHEMBL5570935)
Affinity DataIC50: 113nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643746(CHEMBL5573833)
Affinity DataIC50: 141nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643755(CHEMBL5595371)
Affinity DataIC50: 144nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643753(CHEMBL5574838)
Affinity DataIC50: 159nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643785(CHEMBL5566154)
Affinity DataIC50: 163nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643754(CHEMBL5571155)
Affinity DataIC50: 183nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643786(CHEMBL5570186)
Affinity DataIC50: 255nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643777(CHEMBL5569689)
Affinity DataIC50: 377nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643774(CHEMBL5570481)
Affinity DataIC50: 615nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643775(CHEMBL5571502)
Affinity DataIC50: 1.00E+3nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643756(CHEMBL5574907)
Affinity DataIC50: 1.30E+3nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643747(CHEMBL5570348)
Affinity DataIC50: 1.00E+4nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCyclic AMP-dependent transcription factor ATF-4(Human)
Denali Therapeutics Inc.

Curated by ChEMBL
LigandPNGBDBM50643745(CHEMBL5564460)
Affinity DataIC50: 1.00E+4nMAssay Description:Activation of ATF4 ( unknown origin) expressed in human H4 cells incubated for 24 hrs by reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed