Report error Found 125 Enz. Inhib. hit(s) with all data for entry = 50019784
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human Cav3.2 expressed in HEK293T cells assessed as inhibition of channel current by whole cell patch clamp analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human recombinant Cav3.2 alpha1 subunit expressed in HEK293T cells assessed as inhibition of calcium influx measured for 300 secs by FL...More data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human recombinant Cav3.2 alpha1 subunit expressed in HEK293T cells assessed as inhibition of calcium influx measured for 300 secs by FL...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 2.43E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human recombinant Cav3.2 alpha1 subunit expressed in HEK293T cells assessed as inhibition of calcium influx measured for 300 secs by FL...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 3.09E+4nMAssay Description:Inhibition of human recombinant Cav3.2 alpha1 subunit expressed in HEK293T cells assessed as inhibition of calcium influx measured for 300 secs by FL...More data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human Cav2.2 expressed in HEK293T cells assessed as inhibition of channel current by whole cell patch clamp analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant Cav3.2 alpha1 subunit expressed in HEK293T cells assessed as inhibition of calcium influx measured for 300 secs by FL...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 4.90E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of human recombinant Cav3.2 alpha1 subunit expressed in HEK293T cells assessed as inhibition of calcium influx measured for 300 secs by FL...More data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of human recombinant Cav3.2 alpha1 subunit expressed in HEK293T cells assessed as inhibition of calcium influx measured for 300 secs by FL...More data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University
Curated by ChEMBL
Monash University
Curated by ChEMBL
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair
Ligand InfoSimilars











































