Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50019632
TargetCholinesterase(Horse)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8961BDBM8961(CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8960BDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual specificity protein kinase CLK1(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621213BDBM50621213(CHEMBL5410811)
Affinity DataIC50: 17nMAssay Description:Inhibition of human CLK1 using ERMRPRKRQGSVRRRV as substrate incubated for 40 mins in presence of Mg/[gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621200BDBM50621200(CHEMBL5402840)
Affinity DataIC50: 27nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621215BDBM50621215(CHEMBL5408228)
Affinity DataIC50: 33nMAssay Description:Inhibition of human CLK1 using ERMRPRKRQGSVRRRV as substrate incubated for 40 mins in presence of Mg/[gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621214BDBM50621214(CHEMBL5410094)
Affinity DataIC50: 39nMAssay Description:Inhibition of human CLK1 using ERMRPRKRQGSVRRRV as substrate incubated for 40 mins in presence of Mg/[gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621217BDBM50621217(CHEMBL5428809)
Affinity DataIC50: 40nMAssay Description:Inhibition of human CLK1 using ERMRPRKRQGSVRRRV as substrate incubated for 40 mins in presence of Mg/[gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50445253BDBM50445253(CHEMBL1232500)
Affinity DataIC50: 44nMAssay Description:Inhibition of CLK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621212BDBM50621212(CHEMBL5403328)
Affinity DataIC50: 54nMAssay Description:Inhibition of human CLK1 using ERMRPRKRQGSVRRRV as substrate incubated for 40 mins in presence of Mg/[gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621196BDBM50621196(CHEMBL5396284)
Affinity DataIC50: 68nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621216BDBM50621216(CHEMBL5412688)
Affinity DataIC50: 76nMAssay Description:Inhibition of human CLK1 using ERMRPRKRQGSVRRRV as substrate incubated for 40 mins in presence of Mg/[gamma-33P]-ATP by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621213BDBM50621213(CHEMBL5410811)
Affinity DataIC50: 106nMAssay Description:Inhibition of human DYRK1A using RRRFRPASPLRGPPK as substrate incubated for 40 mins in presence of Mg/[gamma-33P]-ATP by scintillation counting metho...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621199BDBM50621199(CHEMBL5417812)
Affinity DataIC50: 154nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50445253BDBM50445253(CHEMBL1232500)
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant GST-fused human DYRK1A expressed in Escherichia coli using myelin basic protein as substrate incubated for 10 mins by liqui...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621214BDBM50621214(CHEMBL5410094)
Affinity DataIC50: 429nMAssay Description:Inhibition of human DYRK1A using RRRFRPASPLRGPPK as substrate incubated for 40 mins in presence of Mg/[gamma-33P]-ATP by scintillation counting metho...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621197BDBM50621197(CHEMBL5408824)
Affinity DataIC50: 439nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621206BDBM50621206(CHEMBL5402721)
Affinity DataIC50: 470nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621212BDBM50621212(CHEMBL5403328)
Affinity DataIC50: 529nMAssay Description:Inhibition of human DYRK1A using RRRFRPASPLRGPPK as substrate incubated for 40 mins in presence of Mg/[gamma-33P]-ATP by scintillation counting metho...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621202BDBM50621202(CHEMBL5408141)
Affinity DataIC50: 703nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621201BDBM50621201(CHEMBL5397089)
Affinity DataIC50: 761nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621203BDBM50621203(CHEMBL5398338)
Affinity DataIC50: 821nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621216BDBM50621216(CHEMBL5412688)
Affinity DataIC50: 883nMAssay Description:Inhibition of human DYRK1A using RRRFRPASPLRGPPK as substrate incubated for 40 mins in presence of Mg/[gamma-33P]-ATP by scintillation counting metho...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621215BDBM50621215(CHEMBL5408228)
Affinity DataIC50: 885nMAssay Description:Inhibition of human DYRK1A using RRRFRPASPLRGPPK as substrate incubated for 40 mins in presence of Mg/[gamma-33P]-ATP by scintillation counting metho...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621198BDBM50621198(CHEMBL5398767)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621209BDBM50621209(CHEMBL5407180)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621205BDBM50621205(CHEMBL5428725)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621211BDBM50621211(CHEMBL5407164)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621204BDBM50621204(CHEMBL5440931)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621207BDBM50621207(CHEMBL5412852)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621195BDBM50621195(CHEMBL5400482)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621208BDBM50621208(CHEMBL5414144)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621210BDBM50621210(CHEMBL5434888)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621208BDBM50621208(CHEMBL5414144)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured eve...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621209BDBM50621209(CHEMBL5407180)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621211BDBM50621211(CHEMBL5407164)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Rouen Normandy

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621210BDBM50621210(CHEMBL5434888)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human erythrocyte AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed