Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50020908
TargetSerine/threonine-protein kinase Chk1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50634755(CHEMBL5512468)
Affinity DataIC50: 0.550nMAssay Description:Inhibition of CHK1 (unknown origin) preincubated with compound for 10 mins followed by ATP addition and measured after 50 mins by fluorescence based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50524300(LY2606368 | Prexasertib | US11564920, Example Prex...)
Affinity DataIC50: 1nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM328993(US9663503, Compound 1 | 5-[[4-[[(2R)-morpholin-2-y...)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of CHK1 (unknown origin) preincubated with compound for 10 mins followed by ATP addition and measured after 50 mins by fluorescence based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50634757(CHEMBL5542176)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of CHK1 (unknown origin) preincubated with compound for 10 mins followed by ATP addition and measured after 50 mins by fluorescence based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk2(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50524300(LY2606368 | Prexasertib | US11564920, Example Prex...)
Affinity DataIC50: 8nMAssay Description:Inhibition of CHK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50634754(CHEMBL5527983)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of CHK1 (unknown origin) preincubated with compound for 10 mins followed by ATP addition and measured after 50 mins by fluorescence based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50634758(CHEMBL5559032)
Affinity DataIC50: 12nMAssay Description:Inhibition of CHK1 (unknown origin) preincubated with compound for 10 mins followed by ATP addition and measured after 50 mins by fluorescence based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50634753(CHEMBL5532607)
Affinity DataIC50: 42nMAssay Description:Inhibition of CHK1 (unknown origin) preincubated with compound for 10 mins followed by ATP addition and measured after 50 mins by fluorescence based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50634756(CHEMBL5559220)
Affinity DataIC50: 42nMAssay Description:Inhibition of CHK1 (unknown origin) preincubated with compound for 10 mins followed by ATP addition and measured after 50 mins by fluorescence based ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed