Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50020913
TargetAcetylcholinesterase(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634776(Donepezil | Donepezilo | D-797 | Donaz)
Affinity DataIC50: 18nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured after 10 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634776(Donepezil | Donepezilo | D-797 | Donaz)
Affinity DataIC50: 21nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50433314([14C]-Tacrine Monohydrate Monohydrochloride | CHEM...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured after 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634775(CHEMBL5557312)
Affinity DataKi:  27nMAssay Description:Mixed-type inhibition of equine serum BChE using varying concentrations of butyrylthiocholine iodide as substrate assessed as inhibition constant by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50433314([14C]-Tacrine Monohydrate Monohydrochloride | CHEM...)
Affinity DataIC50: 30nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50433314([14C]-Tacrine Monohydrate Monohydrochloride | CHEM...)
Affinity DataKd:  49nMAssay Description:Binding affinity to equine BChE in phosphate buffer at pH 8 assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634775(CHEMBL5557312)
Affinity DataKd:  62nMAssay Description:Binding affinity to equine BChE in phosphate buffer at pH 8 assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634775(CHEMBL5557312)
Affinity DataIC50: 65nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634775(CHEMBL5557312)
Affinity DataIC50: 72nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured after 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50433314([14C]-Tacrine Monohydrate Monohydrochloride | CHEM...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured after 10 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634788(CHEMBL5558492)
Affinity DataKd:  148nMAssay Description:Binding affinity to equine BChE in phosphate buffer at pH 8 assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634788(CHEMBL5558492)
Affinity DataIC50: 163nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634788(CHEMBL5558492)
Affinity DataIC50: 190nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured after 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50433314([14C]-Tacrine Monohydrate Monohydrochloride | CHEM...)
Affinity DataIC50: 290nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634773(CHEMBL5555131)
Affinity DataIC50: 396nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634773(CHEMBL5555131)
Affinity DataIC50: 402nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634772(CHEMBL5556474)
Affinity DataIC50: 430nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634784(CHEMBL5532251)
Affinity DataIC50: 466nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634787(CHEMBL5557952)
Affinity DataIC50: 528nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634779(CHEMBL5517704)
Affinity DataIC50: 717nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634778(CHEMBL5532599)
Affinity DataKd:  759nMAssay Description:Binding affinity to equine BChE in phosphate buffer at pH 8 assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634778(CHEMBL5532599)
Affinity DataIC50: 765nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634769(CHEMBL5555332)
Affinity DataIC50: 906nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634780(CHEMBL5542859)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634771(CHEMBL5532253)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634781(CHEMBL5556994)
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634772(CHEMBL5556474)
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634774(CHEMBL5559422)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634785(CHEMBL5505916)
Affinity DataIC50: 1.92E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634768(CHEMBL5557601)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634776(Donepezil | Donepezilo | D-797 | Donaz)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634771(CHEMBL5532253)
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634783(CHEMBL5532065)
Affinity DataIC50: 4.92E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634769(CHEMBL5555332)
Affinity DataIC50: 4.94E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634776(Donepezil | Donepezilo | D-797 | Donaz)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured after 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634777(CHEMBL5517644)
Affinity DataIC50: 5.52E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634786(CHEMBL5512595)
Affinity DataIC50: 5.79E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634775(CHEMBL5557312)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634770(CHEMBL5542336)
Affinity DataIC50: 6.57E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634770(CHEMBL5542336)
Affinity DataIC50: 6.59E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634774(CHEMBL5559422)
Affinity DataIC50: 7.06E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634776(Donepezil | Donepezilo | D-797 | Donaz)
Affinity DataKd:  7.20E+3nMAssay Description:Binding affinity to equine BChE in phosphate buffer at pH 8 assessed as equilibrium dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634768(CHEMBL5557601)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634782(CHEMBL5532475)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634767(CHEMBL5512467)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50634767(CHEMBL5512467)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed