Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50021786
LigandChemical structure of BindingDB Monomer ID 50644906BDBM50644906(CHEMBL5574087)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50637886BDBM50637886(Culmerciclib)
Affinity DataIC50: 0.350nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50644904BDBM50644904(CHEMBL5583721)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50644906BDBM50644906(CHEMBL5574087)
Affinity DataIC50: 0.390nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50637886BDBM50637886(Culmerciclib)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50644904BDBM50644904(CHEMBL5583721)
Affinity DataIC50: 0.520nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50644907BDBM50644907(CHEMBL5566684)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50644905BDBM50644905(CHEMBL5570615)
Affinity DataIC50: 0.650nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50644907BDBM50644907(CHEMBL5566684)
Affinity DataIC50: 0.730nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50644903BDBM50644903(Eciruciclib)
Affinity DataIC50: 0.840nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50644905BDBM50644905(CHEMBL5570615)
Affinity DataIC50: 0.890nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 6309BDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 0.990nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50110183BDBM50110183(Abemaciclib | LY-2835219 | US10696678, Example LY2...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50110183BDBM50110183(Abemaciclib | LY-2835219 | US10696678, Example LY2...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50644903BDBM50644903(Eciruciclib)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 6309BDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 3nMAssay Description:Inhibition of CDK6/Cyclin D1 in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50110183BDBM50110183(Abemaciclib | LY-2835219 | US10696678, Example LY2...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of CDK4/Cyclin D1 in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50644908BDBM50644908(CHEMBL5584075)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 6309BDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50637886BDBM50637886(Culmerciclib)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin) transfected in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50644908BDBM50644908(CHEMBL5584075)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 6309BDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 6.90nMAssay Description:Inhibition of CDK4/Cyclin D1 in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50110183BDBM50110183(Abemaciclib | LY-2835219 | US10696678, Example LY2...)
Affinity DataIC50: 7nMAssay Description:Inhibition of CDK6/Cyclin D1 in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50644902BDBM50644902(CHEMBL5567106)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50644909BDBM50644909(CHEMBL5575895)
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50644902BDBM50644902(CHEMBL5567106)
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50637886BDBM50637886(Culmerciclib)
Affinity DataIC50: 13nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) in presence of 33P-gamma-ATP by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50644909BDBM50644909(CHEMBL5575895)
Affinity DataIC50: 21nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 6309BDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 27nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin) transfected in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 6309BDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 32nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin) transfected in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50637886BDBM50637886(Culmerciclib)
Affinity DataIC50: 35nMAssay Description:Inhibition of CDK5/p25 (unknown origin) in presence of 33P-gamma-ATP by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 148264BDBM148264(US8962630, 74 | Ribociclib | LEE011 | Kisqali | 7-...)
Affinity DataIC50: 51nMAssay Description:Inhibition of CDK4/Cyclin D1 in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50644901BDBM50644901(CHEMBL5589797)
Affinity DataIC50: 52nMAssay Description:Inhibition of CDK4/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50637886BDBM50637886(Culmerciclib)
Affinity DataIC50: 60nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin) transfected in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 148264BDBM148264(US8962630, 74 | Ribociclib | LEE011 | Kisqali | 7-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of CDK6/Cyclin D1 in human MCF7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50644901BDBM50644901(CHEMBL5589797)
Affinity DataIC50: 78nMAssay Description:Inhibition of CDK6/Cyclin D1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50637886BDBM50637886(Culmerciclib)
Affinity DataIC50: 246nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin) in presence of 33P-gamma-ATP by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50637886BDBM50637886(Culmerciclib)
Affinity DataIC50: 556nMAssay Description:Inhibition of CDK2/Cyclin E1 (unknown origin) transfected in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50637886BDBM50637886(Culmerciclib)
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of CDK1/Cyclin E1 (unknown origin) transfected in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 6309BDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2/Cyclin E1 (unknown origin) transfected in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 6309BDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK1/Cyclin E1 (unknown origin) transfected in HEK293 cells by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed