Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50021746
Affinity DataKd: 40nMAssay Description:Binding affinity to TTR V30M mutant (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Affinity DataKd: 42nMAssay Description:Binding affinity to TTR V30M mutant (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Affinity DataKd: 53nMAssay Description:Binding affinity to TTR V30M mutant (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKd: 66nMAssay Description:Binding affinity to TTR V30M mutant (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Affinity DataKd: 78nMAssay Description:Binding affinity to TTR V30M mutant (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Affinity DataKd: 120nMAssay Description:Binding affinity to TTR V30M mutant (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Affinity DataKd: 138nMAssay Description:Binding affinity to TTR V30M mutant (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+3nMAssay Description:Binding affinity to TTR in human plasma assessed as target occupancy incubated for 6 hrs in presence of E)-S-phenyl 3-(4-hydroxy-3,5-dimethyistyryl)b...More data for this Ligand-Target Pair
Affinity DataEC50: 2.70E+3nMAssay Description:Binding affinity to TTR in human plasma assessed as target occupancy incubated for 6 hrs in presence of E)-S-phenyl 3-(4-hydroxy-3,5-dimethyistyryl)b...More data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+3nMAssay Description:Binding affinity to TTR in human plasma assessed as target occupancy incubated for 6 hrs in presence of E)-S-phenyl 3-(4-hydroxy-3,5-dimethyistyryl)b...More data for this Ligand-Target Pair
Affinity DataEC50: 3.50E+3nMAssay Description:Binding affinity to TTR in human plasma assessed as target occupancy incubated for 6 hrs in presence of E)-S-phenyl 3-(4-hydroxy-3,5-dimethyistyryl)b...More data for this Ligand-Target Pair
Affinity DataEC50: 3.90E+3nMAssay Description:Binding affinity to TTR in human plasma assessed as target occupancy incubated for 6 hrs in presence of E)-S-phenyl 3-(4-hydroxy-3,5-dimethyistyryl)b...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of acid-induced TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by acetate buffer at pH 4.7 addition and me...More data for this Ligand-Target Pair
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of acid-induced TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by acetate buffer at pH 4.7 addition and me...More data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of acid-induced TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by acetate buffer at pH 4.7 addition and me...More data for this Ligand-Target Pair
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of acid-induced TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by acetate buffer at pH 4.7 addition and me...More data for this Ligand-Target Pair
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of acid-induced TTR V30M mutant (unknown origin) aggregation preincubated for 30 mins followed by acetate buffer at pH 4.7 addition and me...More data for this Ligand-Target Pair
Affinity DataEC50: 8.90E+3nMAssay Description:Binding affinity to TTR in human plasma assessed as target occupancy incubated for 6 hrs in presence of E)-S-phenyl 3-(4-hydroxy-3,5-dimethyistyryl)b...More data for this Ligand-Target Pair
Affinity DataEC50: 1.56E+4nMAssay Description:Binding affinity to TTR in human plasma assessed as target occupancy incubated for 6 hrs in presence of E)-S-phenyl 3-(4-hydroxy-3,5-dimethyistyryl)b...More data for this Ligand-Target Pair
