Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50021348
TargetSon of sevenless homolog 1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639756BDBM50639756(CHEMBL5561874)
Affinity DataIC50: 40nMAssay Description:Inhibition of SOS1 (unknown origin) mediated KRAS activation by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSon of sevenless homolog 1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581659BDBM50581659(CHEMBL4519023 | US20230339952, Comparative Compoun...)
Affinity DataIC50: 41nMAssay Description:Inhibition of SOS1 (unknown origin) mediated KRAS activation by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSon of sevenless homolog 1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639755BDBM50639755(CHEMBL5559965)
Affinity DataIC50: 86nMAssay Description:Inhibition of SOS1 (unknown origin) mediated KRAS activation by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSon of sevenless homolog 1(Human)
Nanjing University of Chinese Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639757BDBM50639757(CHEMBL5567725)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of SOS1 (unknown origin) mediated KRAS activation by HTRF methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed