Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50021075
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50636536(CHEMBL5559782)
Affinity DataEC50:  150nMAssay Description:Agonist activity at mouse PIEZO1 transfected in HEK293-T-REx cells assessed as activation of intracellular Ca2+ levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50636537(CHEMBL5560055)
Affinity DataEC50:  280nMAssay Description:Agonist activity at mouse PIEZO1 transfected in HEK293-T-REx cells assessed as activation of intracellular Ca2+ levelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Human)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50636550(CHEMBL5557661)
Affinity DataEC50:  400nMAssay Description:Agonist activity at human PIEZO1 overexpressing HEK293-A cells co-expressing mCherry-piezo1 assessed as induction of calcium influx by fluo-3 based r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Human)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50636549(CHEMBL5517966)
Affinity DataEC50:  460nMAssay Description:Agonist activity at human PIEZO1 overexpressing HEK293-A cells co-expressing mCherry-piezo1 assessed as induction of calcium influx by fluo-3 based r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Human)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50600401(CHEMBL4303374)
Affinity DataEC50:  500nMAssay Description:Agonist activity at human PIEZO1 overexpressing HEK293-A cells co-expressing mCherry-piezo1 assessed as induction of calcium influx by fluo-3 based r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Human)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50636546(CHEMBL5557001)
Affinity DataEC50:  550nMAssay Description:Agonist activity at human PIEZO1 overexpressing HEK293-A cells co-expressing mCherry-piezo1 assessed as induction of calcium influx by fluo-3 based r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Human)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50636539(CHEMBL5559656)
Affinity DataEC50:  570nMAssay Description:Agonist activity at human PIEZO1 overexpressing HEK293-A cells co-expressing mCherry-piezo1 assessed as induction of calcium influx by fluo-3 based r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Mouse)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50600401(CHEMBL4303374)
Affinity DataEC50:  600nMAssay Description:Agonist activity at mouse PIEZO1 transfected in HEK293-T-REx cells assessed as activation of intracellular Ca2+ levelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Human)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50636548(CHEMBL5559157)
Affinity DataEC50:  600nMAssay Description:Agonist activity at human PIEZO1 overexpressing HEK293-A cells co-expressing mCherry-piezo1 assessed as induction of calcium influx by fluo-3 based r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Human)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50636547(CHEMBL5523571)
Affinity DataEC50:  880nMAssay Description:Agonist activity at human PIEZO1 overexpressing HEK293-A cells co-expressing mCherry-piezo1 assessed as induction of calcium influx by fluo-3 based r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Human)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50636545(CHEMBL5568319)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human PIEZO1 overexpressing HEK293-A cells co-expressing mCherry-piezo1 assessed as induction of calcium influx by fluo-3 based r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Human)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50636542(CHEMBL5562183)
Affinity DataEC50:  1.04E+3nMAssay Description:Agonist activity at human PIEZO1 overexpressing HEK293-A cells co-expressing mCherry-piezo1 assessed as induction of calcium influx by fluo-3 based r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Human)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50636541(CHEMBL5560993)
Affinity DataEC50:  1.09E+3nMAssay Description:Agonist activity at human PIEZO1 overexpressing HEK293-A cells co-expressing mCherry-piezo1 assessed as induction of calcium influx by fluo-3 based r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Human)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50636538(CHEMBL5567510)
Affinity DataEC50:  1.34E+3nMAssay Description:Agonist activity at human PIEZO1 overexpressing HEK293-A cells co-expressing mCherry-piezo1 assessed as induction of calcium influx by fluo-3 based r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Human)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50636544(CHEMBL5542789)
Affinity DataEC50:  2.06E+3nMAssay Description:Agonist activity at human PIEZO1 overexpressing HEK293-A cells co-expressing mCherry-piezo1 assessed as induction of calcium influx by fluo-3 based r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Human)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50636540(CHEMBL5549987)
Affinity DataEC50:  2.10E+3nMAssay Description:Agonist activity at human PIEZO1 overexpressing HEK293-A cells co-expressing mCherry-piezo1 assessed as induction of calcium influx by fluo-3 based r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPiezo-type mechanosensitive ion channel component 1(Human)
CSIR-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50636543(CHEMBL5564574)
Affinity DataEC50:  9.90E+3nMAssay Description:Agonist activity at human PIEZO1 overexpressing HEK293-A cells co-expressing mCherry-piezo1 assessed as induction of calcium influx by fluo-3 based r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed