Compile Data Set for Download or QSAR
Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 50022017
TargetALK tyrosine kinase receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647283(CHEMBL5598386)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647284(CHEMBL5590922)
Affinity DataIC50: 0.330nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50456923(CHEMBL4213353)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of PI3K alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647289(CHEMBL5597640)
Affinity DataIC50: 0.710nMAssay Description:Inhibition of c-Met (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647279(CHEMBL5596808)
Affinity DataIC50: 0.790nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50172080(CHEMBL3808948)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647285(CHEMBL5596179)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647286(CHEMBL5596051)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647269(CHEMBL5597352)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50555924(CHEMBL4758378)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647268(CHEMBL5596073)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647290(CHEMBL5597086)
Affinity DataIC50: 7nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647269(CHEMBL5597352)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647268(CHEMBL5596073)
Affinity DataIC50: 7.90nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50638120(CHEMBL5518098)
Affinity DataIC50: 8nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647278(CHEMBL5598379)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647271(CHEMBL5596801)
Affinity DataIC50: 8.60nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647281(CHEMBL5597117)
Affinity DataIC50: 10nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647271(CHEMBL5596801)
Affinity DataIC50: 10nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 11nMAssay Description:Inhibition of PI3K alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM261686(US9708295, 27)
Affinity DataIC50: 13nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50610587(CHEMBL5269169)
Affinity DataIC50: 13nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647273(CHEMBL5598343)
Affinity DataIC50: 14nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM261686(US9708295, 27)
Affinity DataIC50: 14nMAssay Description:Inhibition of ALK (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647282(CHEMBL5597495)
Affinity DataIC50: 14nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM179801(3-((2,6-dichloro-3-fluorophenyl)thio)-5-(1-(piperi...)
Affinity DataIC50: 15nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50172080(CHEMBL3808948)
Affinity DataIC50: 15nMAssay Description:Inhibition of FGFR3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50172080(CHEMBL3808948)
Affinity DataIC50: 17nMAssay Description:Inhibition of FGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647272(CHEMBL5598344)
Affinity DataIC50: 17nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50555924(CHEMBL4758378)
Affinity DataIC50: 18nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50172080(CHEMBL3808948)
Affinity DataIC50: 18nMAssay Description:Inhibition of FGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647287(CHEMBL5597248)
Affinity DataIC50: 20nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647282(CHEMBL5597495)
Affinity DataIC50: 25nMAssay Description:Inhibition of TRKB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647270(CHEMBL5596908)
Affinity DataIC50: 26nMAssay Description:Inhibition of AXL (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50610587(CHEMBL5269169)
Affinity DataIC50: 27nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647282(CHEMBL5597495)
Affinity DataIC50: 28nMAssay Description:Inhibition of TRKA (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)
Affinity DataIC50: 28nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647270(CHEMBL5596908)
Affinity DataIC50: 32nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM180270(US9133162, Example 1)
Affinity DataIC50: 33nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647280(CHEMBL5596702)
Affinity DataIC50: 34nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647289(CHEMBL5597640)
Affinity DataIC50: 38nMAssay Description:Inhibition of HDAC1 (unknown origin) expressed in Sf9 cells using Z-Lys(Ac)-AMC as fluorogenic substrate preincubated for 60 mins followed by substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647267(CHEMBL5596227)
Affinity DataIC50: 40nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647267(CHEMBL5596227)
Affinity DataIC50: 60nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647288(CHEMBL5597403)
Affinity DataIC50: 65nMAssay Description:Inhibition of wildtype EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647276(CHEMBL5598465)
Affinity DataIC50: 110nMAssay Description:Inhibition of PIM-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647277(CHEMBL5597950)
Affinity DataIC50: 123nMAssay Description:Inhibition of PIM-1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM179801(3-((2,6-dichloro-3-fluorophenyl)thio)-5-(1-(piperi...)
Affinity DataIC50: 135nMAssay Description:Inhibition of ALK (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647272(CHEMBL5598344)
Affinity DataIC50: 147nMAssay Description:Inhibition of c-MET (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Liaoning University

Curated by ChEMBL
LigandPNGBDBM50647288(CHEMBL5597403)
Affinity DataIC50: 305nMAssay Description:Inhibition of EGFR L858R/T790M mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
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