Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50022473
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant DYRK2 using KKISGRLSPIMTEQ as substrate incubated for 60 mins in the presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50652735(CHEMBL1254460)
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant DYRK2 using KKISGRLSPIMTEQ as substrate incubated for 60 mins in the presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50291960(CHEMBL1254461)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant DYRK2 using KKISGRLSPIMTEQ as substrate incubated for 60 mins in the presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50431030(CHEMBL379849)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant DYRK2 using KKISGRLSPIMTEQ as substrate incubated for 60 mins in the presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50652735(CHEMBL1254460)
Affinity DataKd:  4.70E+3nMAssay Description:Binding affinity to DYRK2 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50431030(CHEMBL379849)
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to DYRK2 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50291960(CHEMBL1254461)
Affinity DataKd:  7.90E+3nMAssay Description:Binding affinity to DYRK2 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataKd:  1.45E+4nMAssay Description:Binding affinity to DYRK2 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50652736(CHEMBL5647444)
Affinity DataKd:  2.97E+4nMAssay Description:Binding affinity to DYRK2 (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed