Report error Found 60 Enz. Inhib. hit(s) with all data for entry = 50021098
Affinity DataKi: 3.70nMAssay Description:Inhibition of CD73 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of CD73 (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of CD73 (unknown origin)More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1(Human)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of PD-L1 (unknown origin) incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of CD73 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of CD73 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of CD73 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of CD73 (unknown origin) preincubated for 15 mins followed by AMP addition measured after 60 mins by colorimetryMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 38nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of HDAC6 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1(Human)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of PD-L1 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1(Human)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 91nMAssay Description:Inhibition of PD-L1 (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of His-tagged PD-1/PD-L1 (unknown origin) interaction incubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataKd: 101nMAssay Description:Binding affinity to C-terminal 6xHis-tagged recombinant human CD73 (27 to 547 residues) expressed in mammalian expression system assessed as dissocia...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 108nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 131nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 151nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetStromal cell-derived factor 1(Human)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataKd: 160nMAssay Description:Binding affinity to recombinant human CXCL12 expressed in Escherichia coli assessed as dissociation constant incubated for 0.5 hrs by SPR analysisMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1(Human)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataKd: 182nMAssay Description:Binding affinity to recombinant human PD-L1 (1 to 238 residues) extracellular domain expressed in HEK293 cells assessed as dissociation constant by S...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of PD-1/PD-L1 (unknown origin) interaction by HTRF assayMore data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataKd: 368nMAssay Description:Binding affinity to C-terminal polyhis-tagged recombinant mouse PD-L1 (1 to 238 residues) expressed in HEK293 cells assessed as dissociation constant...More data for this Ligand-Target Pair
Affinity DataKd: 565nMAssay Description:Binding affinity to C-terminal 6xHis-tagged recombinant mouse CD73 (29 to 550 residues) expressed in mammalian expression system assessed as dissocia...More data for this Ligand-Target Pair
Affinity DataIC50: 773nMAssay Description:Inhibition of CD73 (unknown origin) preincubated for 15 mins followed by AMP addition measured after 60 mins by colorimetryMore data for this Ligand-Target Pair
TargetNicotinamide phosphoribosyltransferase(Human)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant NAMPT (unknown origin) incubated for 30 mins by absorbance based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CD73 (unknown origin)More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Wenzhou Medical University Lishui Hospital
Curated by ChEMBL
Affinity DataEC50: 1.92E+3nMAssay Description:Inhibition of protein-protein interaction of PD-1 (unknown origin) overexpressed in human Jurkat cells overexpressing NFAT/PD-L1 (unknown origin) ove...More data for this Ligand-Target Pair
Affinity DataIC50: 2.69E+3nMAssay Description:Inhibition of CD73 (unknown origin) preincubated for 15 mins followed by AMP addition measured after 60 mins by colorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 3.11E+3nMAssay Description:Inhibition of CD73 (unknown origin) preincubated for 15 mins followed by AMP addition measured after 60 mins by colorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 5.57E+3nMAssay Description:Inhibition of CD73 (unknown origin) preincubated for 15 mins followed by AMP addition measured after 60 mins by colorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.68E+3nMAssay Description:Inhibition of CD73 (unknown origin) preincubated for 15 mins followed by AMP addition measured after 60 mins by colorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CD73 (unknown origin) preincubated for 15 mins followed by AMP addition measured after 60 mins by colorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CD73 (unknown origin) preincubated for 15 mins followed by AMP addition measured after 60 mins by colorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CD73 (unknown origin) preincubated for 15 mins followed by AMP addition measured after 60 mins by colorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CD73 (unknown origin) preincubated for 15 mins followed by AMP addition measured after 60 mins by colorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CD73 (unknown origin) preincubated for 15 mins followed by AMP addition measured after 60 mins by colorimetryMore data for this Ligand-Target Pair


3D Structure (crystal)



























