Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50022019
LigandPNGBDBM195608(CPI-455 | US20240139197, Compound 3)
Affinity DataIC50: 3nMAssay Description:Inhibition of human full length KDM5B using ART(Kme3)QTARKSTGGKAPRKQLANovaTagPEG-biotin as substrate incubated for 30 to 45 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM191598(KDOAM-20 | KDM5-C49 | 2-(((2-((2-(dimethylamino)et...)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human KDM5B (M1 to R822 residues) expressed in Sf9 cells using 2-OG and histone H3 substrate peptide as substrates preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM195611(GSKJ1)
Affinity DataIC50: 170nMAssay Description:Inhibition of KDM5B (1 to 809 residues) (unknown origin) AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM26113(pyridine-2,4-dicarboxylic acid | cid_10365 | pyrid...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of N-terminal His6/GST-tagged KDM5B catalytic core (1 to 769 residues) (unknown origin) expressed in baculovirus infected High Five cells ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)