Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50021353
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639818BDBM50639818(CHEMBL5532625)
Affinity DataIC50: 9nMAssay Description:Inhibition of P-gp in human Caco-2 cells in presence of paclitaxelMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639801BDBM50639801(CHEMBL5563364)
Affinity DataEC50:  14nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639794BDBM50639794(CHEMBL5542237)
Affinity DataEC50:  19nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639799BDBM50639799(CHEMBL5562926)
Affinity DataEC50:  21nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639818BDBM50639818(CHEMBL5532625)
Affinity DataIC50: 21nMAssay Description:Inhibition of P-gp (unknown origin) ATPase activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639793BDBM50639793(CHEMBL5564317)
Affinity DataEC50:  22nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639808BDBM50639808(CHEMBL5557271)
Affinity DataEC50:  26nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639818BDBM50639818(CHEMBL5532625)
Affinity DataEC50:  28nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50209508BDBM50209508(N-(2-(4-(4-(3,4-dimethoxybenzyl)piperazin-1-yl)phe...)
Affinity DataEC50:  29nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639815BDBM50639815(CHEMBL5563706)
Affinity DataEC50:  30nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639800BDBM50639800(CHEMBL5567740)
Affinity DataEC50:  31nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639797BDBM50639797(CHEMBL5562012)
Affinity DataEC50:  33nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075373BDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 35nMAssay Description:Inhibition of P-gp (unknown origin) ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075373BDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataEC50:  35nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639807BDBM50639807(CHEMBL5567197)
Affinity DataEC50:  39nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639804BDBM50639804(CHEMBL5532631)
Affinity DataEC50:  39nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639813BDBM50639813(CHEMBL5561522)
Affinity DataEC50:  40nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639802BDBM50639802(CHEMBL5566609)
Affinity DataEC50:  43nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639806BDBM50639806(CHEMBL5561197)
Affinity DataEC50:  43nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639811BDBM50639811(CHEMBL5542838)
Affinity DataEC50:  45nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639814BDBM50639814(CHEMBL5559671)
Affinity DataEC50:  51nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075373BDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 53nMAssay Description:Inhibition of P-gp in human Caco-2 cells in presence of paclitaxelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639795BDBM50639795(CHEMBL5561327)
Affinity DataEC50:  55nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639816BDBM50639816(CHEMBL5561243)
Affinity DataEC50:  65nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639796BDBM50639796(CHEMBL5561922)
Affinity DataEC50:  98nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639809BDBM50639809(CHEMBL5561692)
Affinity DataEC50:  108nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639803BDBM50639803(CHEMBL5557171)
Affinity DataEC50:  121nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639812BDBM50639812(CHEMBL5562031)
Affinity DataEC50:  156nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639817BDBM50639817(CHEMBL5566274)
Affinity DataEC50:  167nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639810BDBM50639810(CHEMBL5561737)
Affinity DataEC50:  188nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639817BDBM50639817(CHEMBL5566274)
Affinity DataEC50:  212nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639819BDBM50639819(CHEMBL5542688)
Affinity DataEC50:  221nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639816BDBM50639816(CHEMBL5561243)
Affinity DataEC50:  232nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075373BDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 237nMAssay Description:Inhibition of BCRP (unknown origin) ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639805BDBM50639805(CHEMBL5567370)
Affinity DataEC50:  328nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639798BDBM50639798(CHEMBL5561802)
Affinity DataEC50:  354nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639820BDBM50639820(CHEMBL5565589)
Affinity DataEC50:  422nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639821BDBM50639821(CHEMBL5565658)
Affinity DataEC50:  512nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-dependent translocase ABCB1(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639822BDBM50639822(Ketoconazole | Ketoconazol | Ketoconazolum | J02AB...)
Affinity DataEC50:  1.21E+3nMAssay Description:Inhibition of P-gp in human MES-SA/Dx5 cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639818BDBM50639818(CHEMBL5532625)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of BCRP (unknown origin) ATPase activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-binding cassette sub-family C member 2(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50075373BDBM50075373(CHEMBL348475 | 1N-{4-[2-(6,7-dimethoxy-1,2,3,4-tet...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MRP2 (unknown origin) ATPase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetATP-binding cassette sub-family C member 2(Human)
University of Nebraska Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639818BDBM50639818(CHEMBL5532625)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MRP2 (unknown origin) ATPase activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed