Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50021858
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Takeda Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50507816(Bms-986165 | Deucravacitinib | US12351572, Example...)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Takeda Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50519520(CHEMBL4571117)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Takeda Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50519518(CHEMBL4557190)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Takeda Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50519526(CHEMBL4524832)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of TYK2 (unknown origin) (575 to 869 residues) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Takeda Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50519539(CHEMBL4476261)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of TYK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Takeda Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50530398(CHEMBL4526283)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of TYK2 (unknown origin) (575 to 869 residues) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetIntegrase(Human immunodeficiency virus type 1)
Takeda Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50287594(Asunaprevir | BMS 650032 | BMS-650032)
Affinity DataIC50: 1nMAssay Description:Inhibition of HIV-1 integraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Takeda Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50642723(CHEMBL3125106)
Affinity DataIC50: 2nMAssay Description:Inhibition of HIV-1 integraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Takeda Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50530402(CHEMBL4460194)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of TYK2 (unknown origin) (575 to 869 residues) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Takeda Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50642722(CHEMBL3128331)
Affinity DataIC50: 7nMAssay Description:Inhibition of HIV-1 integraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Takeda Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50645539(CHEMBL5594789)
Affinity DataIC50: 12nMAssay Description:Inhibition of HIV-1 integraseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Takeda Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50183276(6-(3-chloro-2-fluorobenzyl)-1-(2-hydroxyethyl)-4-o...)
Affinity DataIC50: 24nMAssay Description:Inhibition of HIV-1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Takeda Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50519544(CHEMBL4543090)
Affinity DataIC50: 44nMAssay Description:Inhibition of TYK2 (unknown origin) (575 to 869 residues) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Takeda Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50235312(6-(3-chloro-2-fluorobenzyl)-4-oxo-1,4-dihydroquino...)
Affinity DataIC50: 44nMAssay Description:Inhibition of HIV-1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Takeda Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50183277(6-Benzyl-4-oxo-1,4-dihydroquinoline-3-carboxylic A...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of HIV-1 integrase strand transfer activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed