Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50021209
TargetPotassium channel subfamily T member 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50638325(CHEMBL5558979)
Affinity DataIC50: 80nMAssay Description:Inhibition of human KCNT1 (98 to 354 residues) expressed in CHO cells at +60 mV holding potential by whole-cell patch clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50638324(CHEMBL2398613)
Affinity DataIC50: 200nMAssay Description:Inhibition of human KCNT1 (98 to 354 residues) expressed in CHO cells at +60 mV holding potential by whole-cell patch clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50638326(CHEMBL4476393)
Affinity DataIC50: 210nMAssay Description:Inhibition of human KCNT1 (98 to 354 residues) expressed in CHO cells at +60 mV holding potential by whole-cell patch clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPotassium channel subfamily T member 2(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50638326(CHEMBL4476393)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of human KCNT2 expressed in HEK cells at +60 mV holding potential by whole-cell patch clamp electrophysiology methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50638325(CHEMBL5558979)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human KCNT1 (98 to 354 residues) expressed in CHO cells assessed as reduction in thallium fluorescent signal incubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50591533(CHEMBL4449485)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of human KCNT1 (98 to 354 residues) expressed in CHO cells assessed as reduction in thallium fluorescent signal incubated for 15 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50638326(CHEMBL4476393)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human KCNT1 (98 to 354 residues) expressed in CHO cells assessed as reduction in thallium fluorescent signal incubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50638323(CHEMBL3787398)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human KCNT1 (98 to 354 residues) expressed in CHO cells assessed as reduction in thallium fluorescent signal incubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50638324(CHEMBL2398613)
Affinity DataIC50: 1.22E+4nMAssay Description:Inhibition of human KCNT1 (98 to 354 residues) expressed in CHO cells assessed as reduction in thallium fluorescent signal incubated for 15 mins foll...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of human KCNT1 (98 to 354 residues) expressed in CHO cells at +60 mV holding potential by whole-cell patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 2(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human Kv7.2 transiently transfected in CHO cells at -100 mV holding potential by whole-cell patch clamp electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of human KCNT1 expressed in CHO cells by whole-cell patch clamp electrophysiology method relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPotassium channel subfamily T member 1(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50: 1.47E+5nMAssay Description:Inhibition of human KCNT1 (98 to 354 residues) expressed in CHO cells assessed as reduction in thallium fluorescent signal incubated for 15 mins foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed