Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50021223
TargetPresenilin-1(Human)TBA
LigandPNGBDBM50594988(CHEMBL5192892)
Affinity DataIC50: 4nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells expressing wild-type human APP751 assessed as reduction in amyloidbeta42 level measured for 24 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPresenilin-1(Human)TBA
LigandPNGBDBM50458163(CHEMBL4209316)
Affinity DataIC50: 6nMAssay Description:Modulation of human gamma-secretase assessed as reduction in amyloidbeta42 level by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPresenilin-1(Human)TBA
LigandPNGBDBM50534369(E-2212 | E2212)
Affinity DataIC50: 7nMAssay Description:Modulation of human gamma-secretase assessed as reduction in amyloidbeta42 level in plasma by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetPresenilin-1(Human)TBA
LigandPNGBDBM50534362(CHEMBL2151100)
Affinity DataIC50: 10nMAssay Description:Modulation of gamma-secretase in human SH-SY5Y cells assessed as reduction in amyloidbeta42 level measured for 18 hrs by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50364033(CHEMBL1224151)
Affinity DataIC50: 143nMAssay Description:Modulation of human gamma-secretase assessed as reduction in amyloidbeta42 level in plasma by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM193081(US9193726, 69)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of NICD (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed