Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50021867
TargetEpidermal growth factor receptor(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50074743(3-(3-Chloro-phenyl)-5,7-dihydroxy-1H-quinolin-4-on...)
Affinity DataIC50: 8nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50074744(3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-1H-quinoli...)
Affinity DataIC50: 40nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50108771(2-(2-Amino-3-methoxy-phenyl)-chromen-4-one | PD-98...)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of RAF1- induced activation of MEK (unknown origin) signalling pathway assessed as reduction in MEK1 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50108771(2-(2-Amino-3-methoxy-phenyl)-chromen-4-one | PD-98...)
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of RAF1- induced activation of MEK (unknown origin) signalling pathway assessed as reduction in ERK1/2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50645654(CHEMBL5590420)
Affinity DataIC50: 4.35E+3nMAssay Description:Inhibition of RAF1- induced activation of MEK (unknown origin) signalling pathway assessed as reduction in MEK1 phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Palermo

Curated by ChEMBL
LigandPNGBDBM50645654(CHEMBL5590420)
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of RAF1- induced activation of MEK (unknown origin) signalling pathway assessed as reduction in ERK1/2 phosphorylationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed