Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50023440
TargetSphingosine kinase 1(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041978BDBM50041978(CHEMBL3134157)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of SphK1 (unknown origin) by Caliper methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSphingosine kinase 1(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50077142BDBM50077142(CHEMBL3416759)
Affinity DataIC50: 58nMAssay Description:Inhibition of SphK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 1(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663748BDBM50663748(CHEMBL6161512)
Affinity DataIC50: 140nMAssay Description:Inhibition of SphK1(unknown origin0 expressed in human BL-21 cells in presence of ATP by enzymatic inhibition assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 2(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50041978BDBM50041978(CHEMBL3134157)
Affinity DataIC50: 356nMAssay Description:Inhibition of SphK2 (unknown origin) by Caliper methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 1(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50628319BDBM50628319(CHEMBL3815224)
Affinity DataKi:  730nMAssay Description:Inhibition of SphK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 2(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50628319BDBM50628319(CHEMBL3815224)
Affinity DataKi:  900nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 2(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50628319BDBM50628319(CHEMBL3815224)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of SphK2 (unknown origin) using sphingosine as substrate incubated for 30 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 2(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663744BDBM50663744(CHEMBL6150995)
Affinity DataIC50: 3.62E+3nMAssay Description:Inhibition of SphK2 (unknown origin) using sphingosine as substrate incubated for 30 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 1(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240721BDBM50240721((E)-(2S,3R)-2-Dimethylamino-octadec-4-ene-1,3-diol...)
Affinity DataKi:  5.00E+3nMAssay Description:Competitive inhibition of SphK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 2(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663749BDBM50663749(CHEMBL6151244)
Affinity DataKi:  6.50E+3nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 2(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312869BDBM50312869(N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 2(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393642BDBM50393642(CHEMBL2158685)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of SphK2 (unknown origin) assessed as inhibition constant by ADP Quest assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 2(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663748BDBM50663748(CHEMBL6161512)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 2(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50077142BDBM50077142(CHEMBL3416759)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 2(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663745BDBM50663745(CHEMBL6169617)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of SphK2 (unknown origin) using sphingosine as substrate incubated for 30 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 2(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663746BDBM50663746(CHEMBL6171199)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of SphK2 (unknown origin) using sphingosine as substrate incubated for 30 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 2(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393642BDBM50393642(CHEMBL2158685)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of SphK2 (unknown origin) using sphingosine as substrate incubated for 30 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 2(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240721BDBM50240721((E)-(2S,3R)-2-Dimethylamino-octadec-4-ene-1,3-diol...)
Affinity DataKi:  1.20E+4nMAssay Description:Competitive inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 1(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50312869BDBM50312869(N-aryl-4-aryl-1,3-thiazole-2-amine, 5 | CHEMBL1076...)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition of SphK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 2(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50077148BDBM50077148(CHEMBL3416760)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 2(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663743BDBM50663743(CHEMBL6161735)
Affinity DataIC50: 2.03E+4nMAssay Description:Inhibition of SphK2 (unknown origin) using sphingosine as substrate incubated for 30 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 2(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50663747BDBM50663747(CHEMBL6161957)
Affinity DataIC50: 3.59E+4nMAssay Description:Inhibition of SphK2 (unknown origin) using sphingosine as substrate incubated for 30 mins in presence of ATP by ADP-Glo assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSphingosine kinase 1(Human)
Hebei University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50077148BDBM50077148(CHEMBL3416760)
Affinity DataKi:  5.00E+4nMAssay Description:Inhibition of SphK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed