Report error Found 52 Enz. Inhib. hit(s) with all data for entry = 50022177
Affinity DataIC50: 0.5nMAssay Description:Inhibition of SERT in rat cerebral synaptosomes assessed as reduction in [3H]5-HT uptakeMore data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 48nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 59nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 72nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 74nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 78nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 83nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 107nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 135nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 139nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 146nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 152nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 161nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 168nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 242nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 273nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 359nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 467nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.76E+3nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human SERT expressed in HEK293 cells incubated for 30 minsMore data for this Ligand-Target Pair

3D Structure (crystal)


















