Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50021564
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642031(US12344595, Example 78)
Affinity DataEC50:  6nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642027(US12344595, Example 44)
Affinity DataEC50:  12nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642029(US12344595, Example 43)
Affinity DataEC50:  32nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642028(CHEMBL5572064)
Affinity DataEC50:  34nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642013(US12344595, Example 1)
Affinity DataEC50:  42nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50642032(CHEMBL5567368)
Affinity DataIC50: 80nMAssay Description:Inhibition of rat neuronal Nav1.8 by patch clamp electrophysiologyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642014(CHEMBL5566400)
Affinity DataEC50:  110nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642018(CHEMBL5566873)
Affinity DataEC50:  210nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642024(CHEMBL5542424)
Affinity DataEC50:  220nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642030(US12344595, Example 51)
Affinity DataEC50:  240nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642025(US12344595, Example 77)
Affinity DataEC50:  290nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642023(CHEMBL5566116)
Affinity DataEC50:  320nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642022(CHEMBL5569610)
Affinity DataEC50:  860nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642026(US12344595, Example 63)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642017(CHEMBL5566411)
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642020(CHEMBL5542370)
Affinity DataEC50:  9.70E+3nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642021(CHEMBL5566216)
Affinity DataEC50:  1.40E+4nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642016(CHEMBL5570907)
Affinity DataEC50:  2.00E+4nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50642033(CHEMBL5563808)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of rat neuronal Nav1.8 by patch clamp electrophysiologyMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642019(CHEMBL5564191)
Affinity DataEC50:  2.20E+4nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642013(US12344595, Example 1)
Affinity DataEC50:  2.30E+4nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50642013(US12344595, Example 1)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of Cav1.2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642032(CHEMBL5567368)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Nav1.7 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 8 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642013(US12344595, Example 1)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Nav1.6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642033(CHEMBL5563808)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Nav1.7 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642032(CHEMBL5567368)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 2 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642013(US12344595, Example 1)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Nav1.2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 10 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642015(CHEMBL5574136)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of recombinant human Nav1.8 expressed in HEK293 cells by whole cell patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 8 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642033(CHEMBL5563808)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Nav1.6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 8 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642032(CHEMBL5567368)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Nav1.6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642013(US12344595, Example 1)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Merck & Co.

Curated by ChEMBL
LigandPNGBDBM50642033(CHEMBL5563808)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed