Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50021966
TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50646575(CHEMBL5590689)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of EGFR C797S/T790M/L858R mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50646574(CHEMBL5594833)
Affinity DataIC50: 0.290nMAssay Description:Inhibition of EGFR C797S/T790M/Del19 mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50646575(CHEMBL5590689)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of EGFR C797S/T790M/Del19 mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 0.340nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50646574(CHEMBL5594833)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of EGFR C797S/T790M/L858R mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50646573(CHEMBL5590430)
Affinity DataIC50: 0.420nMAssay Description:Inhibition of EGFR C797S/T790M/Del19 mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50646573(CHEMBL5590430)
Affinity DataIC50: 0.610nMAssay Description:Inhibition of EGFR C797S/T790M/L858R mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50646573(CHEMBL5590430)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 6nMAssay Description:Inhibition of EGFR C797S/T790M/L858R mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50185140(AP-26113 | Brigatinib | US11248003, Example Brigat...)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of EGFR C797S/T790M/Del19 mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50646575(CHEMBL5590689)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50646574(CHEMBL5594833)
Affinity DataIC50: 13nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50646575(CHEMBL5590689)
Affinity DataIC50: 61nMAssay Description:Inhibition of wild-type EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50646574(CHEMBL5594833)
Affinity DataIC50: 69nMAssay Description:Inhibition of wild-type EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandPNGBDBM50646573(CHEMBL5590430)
Affinity DataIC50: 71nMAssay Description:Inhibition of wild-type EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed