Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50020974
TargetApoptosis regulator Bcl-2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | Venetoclax | US11420968, Example ABT-199)
Affinity DataKi: <0.0100nMAssay Description:Binding affinity to BCL-W (unknown origin) assessed as inhibition constant by fluorescence polarization binding affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-like protein 1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | Venetoclax | US11420968, Example ABT-199)
Affinity DataKi:  48nMAssay Description:Binding affinity to BCL-xL (unknown origin) assessed as inhibition constant by fluorescence polarization binding affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-like protein 2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | Venetoclax | US11420968, Example ABT-199)
Affinity DataKi:  245nMAssay Description:Binding affinity to BCL-2 (unknown origin) assessed as inhibition constant by fluorescence polarization binding affinity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50610577(CHEMBL5283368)
Affinity DataKi:  400nMAssay Description:Inhibition of BFL-1 (unknown origin)/Bim BH3 peptide (unknown origin) interaction by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50162774(ABT-199 | Venetoclax | US11420968, Example ABT-199)
Affinity DataKi: >444nMAssay Description:Binding affinity to MCL-1 (unknown origin) assessed as inhibition constant by time-resolved fluorescence resonance energy transfer binding affinity a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50635692(CHEMBL5527924)
Affinity DataKi:  1.27E+3nMAssay Description:Binding affinity to BFL-1 C55A mutant (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50635691(CHEMBL5523629)
Affinity DataKi:  1.38E+3nMAssay Description:Binding affinity to BFL-1 C55A mutant (unknown origin) assessed as inhibition constant by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50635691(CHEMBL5523629)
Affinity DataKi:  1.95E+3nMAssay Description:Binding affinity to wild type human BFL-1 assessed as inhibition constant by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBcl-2-related protein A1(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50635692(CHEMBL5527924)
Affinity DataKi:  2.13E+4nMAssay Description:Binding affinity to wild type human BFL-1 assessed as inhibition constant by SPR assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed