Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50021875
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50052428(2-(2,6-Dioxo-piperidin-3-yl)-4,5,6,7-tetrafluoro-i...)
Affinity DataKi:  6.08E+3nMAssay Description:Binding affinity to human CRBN TBD (319 to 425 residues) assessed as inhibition constant by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50070114(CHEMBL468 | 2-(2,6-dioxopiperidin-3-yl)isoindoline...)
Affinity DataKi:  8.55E+3nMAssay Description:Binding affinity to human CRBN TBD (319 to 425 residues) assessed as inhibition constant by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM50630589(CHEMBL5437759)
Affinity DataKi:  3.04E+4nMAssay Description:Binding affinity to human CRBN TBD (319 to 425 residues) assessed as inhibition constant by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProtein cereblon(Human)TBA
LigandPNGBDBM631083(US11802131, Example 10 | N-(2,6-dioxo-3-piperidyl)...)
Affinity DataKi:  6.26E+4nMAssay Description:Binding affinity to human CRBN TBD (319 to 425 residues) assessed as inhibition constant by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed