Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50021822
TargetGTPase KRas(Human)
Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645239BDBM50645239(CHEMBL5573020)
Affinity DataKd:  0.140nMAssay Description:Binding affinity to biotinylated KRAS G12D mutant (unknown origin) incubated for 120 mins by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 672498BDBM672498((5S,8S,11S,15S,18S,23aS,29S,35S,37aS)-8-((S)-sec-b...)
Affinity DataKd:  0.160nMAssay Description:Binding affinity to biotinylated KRAS G12D mutant (unknown origin) incubated for 120 mins by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645244BDBM50645244(CHEMBL5572821)
Affinity DataKd:  0.170nMAssay Description:Binding affinity to biotinylated KRAS G12D mutant (unknown origin) incubated for 120 mins by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 671804BDBM671804((5S,8S,11S,15S,18S,23aS,29S,35S,37aS)-8-((S)-sec-b...)
Affinity DataKd:  0.180nMAssay Description:Binding affinity to biotinylated KRAS G12D mutant (unknown origin) incubated for 120 mins by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645237BDBM50645237(CHEMBL5569602)
Affinity DataKd:  0.190nMAssay Description:Binding affinity to biotinylated KRAS G12D mutant (unknown origin) incubated for 120 mins by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645242BDBM50645242(CHEMBL5575367)
Affinity DataKd:  0.230nMAssay Description:Binding affinity to biotinylated KRAS G12D mutant (unknown origin) incubated for 120 mins by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645243BDBM50645243(CHEMBL5576025)
Affinity DataKd:  0.260nMAssay Description:Binding affinity to biotinylated KRAS G12D mutant (unknown origin) incubated for 120 mins by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645238BDBM50645238(CHEMBL5570375)
Affinity DataKd:  0.320nMAssay Description:Binding affinity to biotinylated KRAS G12D mutant (unknown origin) incubated for 120 mins by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 672505BDBM672505((5S,8S,11S,15S,18S,23aS,29S,35S,37aS)-8-((S)-sec-b...)
Affinity DataKd:  0.470nMAssay Description:Binding affinity to biotinylated KRAS G12D mutant (unknown origin) incubated for 120 mins by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645241BDBM50645241(CHEMBL5572706)
Affinity DataKd:  0.640nMAssay Description:Binding affinity to biotinylated KRAS G12D mutant (unknown origin) incubated for 120 mins by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645240BDBM50645240(CHEMBL5591865)
Affinity DataKd:  0.75nMAssay Description:Binding affinity to biotinylated KRAS G12D mutant (unknown origin) incubated for 120 mins by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645246BDBM50645246(CHEMBL5569112)
Affinity DataKd:  1.10nMAssay Description:Binding affinity to biotinylated KRAS G12D mutant (unknown origin) incubated for 120 mins by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGTPase KRas(Human)
Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50645245BDBM50645245(CHEMBL5566631)
Affinity DataKd:  2.5nMAssay Description:Binding affinity to biotinylated KRAS G12D mutant (unknown origin) incubated for 120 mins by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed