Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50020983
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50042924(CHEMBL1229535)
Affinity DataKi:  7nMAssay Description:Binding affinity to PI3Kgamma (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPhosphatidylinositol 3-kinase regulatory subunit gamma(Homo sapiens)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635722(CHEMBL5537039)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant PI3Kgamma using phosphatidylinositol as substrate in presence of [gamma33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50193013(Duvelisib | INK-1147 | INK-1197 | IPI-145)
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant PI3Kgamma in the presence of ATP by scintillation proximity radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit gamma(Homo sapiens)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635723(CHEMBL5532262)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant PI3Kgamma using phosphatidylinositol as substrate in presence of [gamma33P]ATP by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit gamma(Homo sapiens)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM556970(US11352340, Example 1)
Affinity DataIC50: 50nMAssay Description:Inhibition of P13Kgamma (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635727(CHEMBL5523658)
Affinity DataKd:  63nMAssay Description:Binding affinity to PI3Kgamma (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635719(CHEMBL5557948)
Affinity DataIC50: 100nMAssay Description:Inhibition of PI3Kgamma (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit gamma(Homo sapiens)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635720(CHEMBL5558109)
Affinity DataIC50: 100nMAssay Description:Inhibition of P13Kgamma (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit gamma(Homo sapiens)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM562036(US11396502, Example 12)
Affinity DataIC50: 100nMAssay Description:Inhibition of P13Kgamma (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635722(CHEMBL5537039)
Affinity DataIC50: 110nMAssay Description:Inhibition of P13Kalpha (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635722(CHEMBL5537039)
Affinity DataIC50: 120nMAssay Description:Inhibition of P13Kdelta (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635727(CHEMBL5523658)
Affinity DataIC50: 172nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using peptide as substrate preincubated for 10 mins followed by substrate addition by microplate reader anal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM281486(US9586949, Example 12 | US10022387, Example 12 | U...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human PI3Kgamma expressed in baculovirus infected Sf21 insect cells by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetSmall ribosomal subunit protein eS6(Homo sapiens)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635719(CHEMBL5557948)
Affinity DataIC50: 300nMAssay Description:Inhibition of Ribosomal protein S6 kinase in human THP-1 cells by ELISA analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635723(CHEMBL5532262)
Affinity DataIC50: 300nMAssay Description:Inhibition of P13Kalpha (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635722(CHEMBL5537039)
Affinity DataIC50: 400nMAssay Description:Inhibition of P13Kbeta (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM556970(US11352340, Example 1)
Affinity DataIC50: 500nMAssay Description:Inhibition of P13Kdelta (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635726(CHEMBL5556676)
Affinity DataKd:  600nMAssay Description:Binding affinity to PI3Kgamma (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635723(CHEMBL5532262)
Affinity DataIC50: 730nMAssay Description:Inhibition of P13Kdelta (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635723(CHEMBL5532262)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of P13Kbeta (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635719(CHEMBL5557948)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM562036(US11396502, Example 12)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of P13Kdelta (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635721(CHEMBL5542387)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of P13Kdelta (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635724(CHEMBL5523563)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of P13Kdelta (unknown origin) in the presence of ATP by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50193013(Duvelisib | INK-1147 | INK-1197 | IPI-145)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of N-terminal His-tagged recombinant full-length human PI3Kdelta expressed in baculovirus infected Sf21 insect cells by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635725(CHEMBL5559170)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin) by Scintillation Proximity AssayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635725(CHEMBL5559170)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Hebei University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50635725(CHEMBL5559170)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of P13Kalpha (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed