Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50022123
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 2483BDBM2483(Sustiva | DMP-266 | (4S)-6-chloro-4-(2-cyclopropyl...)
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103642BDBM50103642(CHEMBL308954 | TMC-125 | TMC 125 | 4-(6-amino-5-br...)
Affinity DataIC50: 29nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 222178BDBM222178(Rilpivirine)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648336BDBM50648336(CHEMBL5612140)
Affinity DataIC50: 314nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648339BDBM50648339(CHEMBL5612668)
Affinity DataIC50: 327nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648342BDBM50648342(CHEMBL5613980)
Affinity DataIC50: 410nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648344BDBM50648344(CHEMBL5613406)
Affinity DataIC50: 514nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648335BDBM50648335(CHEMBL5612747)
Affinity DataIC50: 522nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648357BDBM50648357(CHEMBL5612553)
Affinity DataIC50: 527nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648338BDBM50648338(CHEMBL5612529)
Affinity DataIC50: 530nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648354BDBM50648354(CHEMBL5612507)
Affinity DataIC50: 535nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648332BDBM50648332(CHEMBL5612186)
Affinity DataIC50: 582nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648346BDBM50648346(CHEMBL5614187)
Affinity DataIC50: 596nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648352BDBM50648352(CHEMBL5612952)
Affinity DataIC50: 598nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648345BDBM50648345(CHEMBL5612637)
Affinity DataIC50: 622nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648334BDBM50648334(CHEMBL5613851)
Affinity DataIC50: 634nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648348BDBM50648348(CHEMBL5613183)
Affinity DataIC50: 669nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648355BDBM50648355(CHEMBL5613811)
Affinity DataIC50: 676nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648349BDBM50648349(CHEMBL5613123)
Affinity DataIC50: 686nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648347BDBM50648347(CHEMBL5612014)
Affinity DataIC50: 713nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648356BDBM50648356(CHEMBL5612205)
Affinity DataIC50: 718nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648350BDBM50648350(CHEMBL5612631)
Affinity DataIC50: 736nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648351BDBM50648351(CHEMBL5613254)
Affinity DataIC50: 744nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648333BDBM50648333(CHEMBL5611942)
Affinity DataIC50: 769nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648337BDBM50648337(CHEMBL5612451)
Affinity DataIC50: 782nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648343BDBM50648343(CHEMBL5613020)
Affinity DataIC50: 890nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648340BDBM50648340(CHEMBL5613691)
Affinity DataIC50: 990nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 1434BDBM1434(BI-RG-587 | 2-cyclopropyl-7-methyl-2,4,9,15-tetraa...)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648353BDBM50648353(CHEMBL5613297)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Fudan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50648341BDBM50648341(CHEMBL5614024)
Affinity DataIC50: 2.04E+3nMAssay Description:Inhibition of recombinant wild-type HIV-1 reverse transcriptase incubated for 40 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed