Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50022807
TargetTGF-beta receptor type-1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402166BDBM50402166(CHEMBL2207988)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092485BDBM50092485(8-Chloro-4-methyl-1,2,5,6-tetrahydro-pyrido[1,2-a]...)
Affinity DataKi:  2.70nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092492BDBM50092492(4,8-Dimethyl-1,2,5,6-tetrahydro-pyrido[1,2-a]quino...)
Affinity DataKi:  5.80nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149341BDBM50149341(8-Bromo-4-methyl-1,2,5,6-tetrahydro-pyrido[1,2-a]q...)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50402166BDBM50402166(CHEMBL2207988)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50149339BDBM50149339(4-Methyl-8-phenylethynyl-1,2,5,6-tetrahydro-pyrido...)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50092485BDBM50092485(8-Chloro-4-methyl-1,2,5,6-tetrahydro-pyrido[1,2-a]...)
Affinity DataIC50: 41nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
TargetAndrogen receptor(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50228080BDBM50228080(Spiranolactone | S-(2'R,7R,8R,9S,10R,13S,14S)-10,1...)
Affinity DataIC50: 77nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072191BDBM50072191(1,2,5,6-tetrahydro pyrido[1,2-a]quinolin-3-one | 1...)
Affinity DataIC50: 298nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
Hangzhou Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072192BDBM50072192(4,4a,5,6-Tetrahydro-pyrido[1,2-a]quinolin-3-one | ...)
Affinity DataIC50: 5.13E+3nMAssay Description:Inhibition of hypoxia induced HIF1 transcriptional activity in human Hep3B cells by cell-based HRE reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed