Compile Data Set for Download or QSAR
Report error Found 70 Enz. Inhib. hit(s) with all data for entry = 50020985
TargetCytosol aminopeptidase(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50367209(Ubenimex | BESTATIN HYDROCHLORIDE)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human recombinant Leucine aminopeptidase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50635821(CHEMBL5517929)
Affinity DataIC50: 2nMAssay Description:Inhibition of IRAP (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM661078(US20240101542, Compound 25 | (S)-N-hydroxy-3-(4-me...)
Affinity DataIC50: 4nMAssay Description:Inhibition of ERAP2 (unknown origin) using R-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetCytosol aminopeptidase(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50277143(CHR 2797 | CHR-2797 | Tosedostat)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant Leucine aminopeptidase 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLeukotriene A-4 hydrolase(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50277143(CHR 2797 | CHR-2797 | Tosedostat)
Affinity DataIC50: 8nMAssay Description:Inhibition of full length human recombinant Leukotriene A-4 hydrolase expressed in baculovirus infected Insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAminopeptidase N(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50078133(2-Amino-4-methyl-pentane-1-thiol | (S)-2-Amino-4-m...)
Affinity DataIC50: 8nMAssay Description:Inhibition of FLAG-tagged human recombinant Aminopeptidase NMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50: 11nMAssay Description:Inhibition of ERAP2 (unknown origin) using R-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEndoplasmic reticulum aminopeptidase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM661077(US20240101542, Compound 24 | (S)-N-hydroxy-3-(4-me...)
Affinity DataIC50: 19nMAssay Description:Inhibition of ERAP2 (unknown origin) using R-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50: 30nMAssay Description:Inhibition of IRAP (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAminopeptidase N(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50277143(CHR 2797 | CHR-2797 | Tosedostat)
Affinity DataIC50: 30nMAssay Description:Inhibition of FLAG-tagged human recombinant Aminopeptidase NMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50076744(CHEMBL3416733)
Affinity DataIC50: 33nMAssay Description:Inhibition of ERAP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor antagonist protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50353019(CHEMBL1821981)
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant IRAP expressed in baculovirus infected Sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by Michaelis-Men...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM661076(US20240101542, Compound 23 | (S)-N-hydroxy-3-(4-ph...)
Affinity DataIC50: 35nMAssay Description:Inhibition of ERAP2 (unknown origin) using R-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50635821(CHEMBL5517929)
Affinity DataIC50: 37nMAssay Description:Inhibition of ERAP2 (unknown origin) using R-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50635821(CHEMBL5517929)
Affinity DataIC50: 43nMAssay Description:Inhibition of ERAP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM661087(US20240101542, Compound 33 | (3S)-4-(4-hydroxyphen...)
Affinity DataIC50: 84nMAssay Description:Inhibition of IRAP (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50078133(2-Amino-4-methyl-pentane-1-thiol | (S)-2-Amino-4-m...)
Affinity DataIC50: 110nMAssay Description:Inhibition of C-terminal Hexa-histidine-tagged human recombinant ERAP1 expressed in Sf9 cells using L-AMC as substrate incubated for 15 mins by Micha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50353018(CHEMBL1821980 | CHEMBL1852660)
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant IRAP expressed in baculovirus infected Sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by Michaelis-Men...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50245355(CHEMBL4070078)
Affinity DataIC50: 129nMAssay Description:Inhibition of ERAP2 (unknown origin) using R-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM661078(US20240101542, Compound 25 | (S)-N-hydroxy-3-(4-me...)
Affinity DataIC50: 186nMAssay Description:Inhibition of IRAP (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetLeukotriene A-4 hydrolase(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50367209(Ubenimex | BESTATIN HYDROCHLORIDE)
Affinity DataIC50: 200nMAssay Description:Inhibition of full length human recombinant Leukotriene A-4 hydrolase expressed in baculovirus infected Insect cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50190107(CHEMBL3827468)
Affinity DataIC50: 218nMAssay Description:Inhibition of IRAP (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50635820(CHEMBL5512491)
Affinity DataIC50: 344nMAssay Description:Inhibition of IRAP (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM661077(US20240101542, Compound 24 | (S)-N-hydroxy-3-(4-me...)
Affinity DataIC50: 383nMAssay Description:Inhibition of IRAP (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50353018(CHEMBL1821980 | CHEMBL1852660)
Affinity DataIC50: 390nMAssay Description:Inhibition of human recombinant ERAP2 expressed in baculovirus infected sf9 cells using R-AMC as substrate incubated for 5 to 10 mins by Michaelis-Me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50635820(CHEMBL5512491)
Affinity DataIC50: 513nMAssay Description:Inhibition of ERAP1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50190107(CHEMBL3827468)
Affinity DataIC50: 520nMAssay Description:Inhibition of ERAP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50190107(CHEMBL3827468)
Affinity DataIC50: 547nMAssay Description:Inhibition of ERAP2 (unknown origin) using R-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM661076(US20240101542, Compound 23 | (S)-N-hydroxy-3-(4-ph...)
Affinity DataIC50: 560nMAssay Description:Inhibition of IRAP (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50635820(CHEMBL5512491)
Affinity DataIC50: 571nMAssay Description:Inhibition of ERAP2 (unknown origin) using R-AMC as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50078133(2-Amino-4-methyl-pentane-1-thiol | (S)-2-Amino-4-m...)
Affinity DataIC50: 610nMAssay Description:Inhibition of C-terminal Hexa-histidine-tagged human recombinant ERAP2 expressed in Sf9 cells using R-AMC as substrate incubated for 15 mins by Micha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50277143(CHR 2797 | CHR-2797 | Tosedostat)
Affinity DataIC50: 770nMAssay Description:Inhibition of C-terminal Hexa-histidine-tagged human recombinant ERAP2 expressed in Sf9 cells using R-AMC as substrate incubated for 15 mins by Micha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM661087(US20240101542, Compound 33 | (3S)-4-(4-hydroxyphen...)
Affinity DataIC50: 850nMAssay Description:Inhibition of ERAP2 (unknown origin) using R-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50353018(CHEMBL1821980 | CHEMBL1852660)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant ERAP1 expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by Michaelis-Me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50570847(CHEMBL4863168)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of ERAP2 (unknown origin) using R-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50245355(CHEMBL4070078)
Affinity DataIC50: 1.75E+3nMAssay Description:Inhibition of IRAP (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50078825(phenyl(phenylsulfonyl)amine | N-Phenyl-benzenesulf...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of IRAP (unknown origin) using L-pNA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50570847(CHEMBL4863168)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of IRAP (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor antagonist protein(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50353016(CHEMBL1821978)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant IRAP expressed in baculovirus infected Sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by Michaelis-Men...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAminopeptidase N(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50367209(Ubenimex | BESTATIN HYDROCHLORIDE)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of FLAG-tagged human recombinant Aminopeptidase NMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50353019(CHEMBL1821981)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant ERAP2 expressed in baculovirus infected sf9 cells using R-AMC as substrate incubated for 5 to 10 mins by Michaelis-Me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50635824(CHEMBL5518024)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of ERAP1 (unknown origin) using L-pNA as susbtrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50635823(CHEMBL5558960)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of ERAP1 (unknown origin) using WRCYEKMALK as substrate by Michaelis-Menten analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50570847(CHEMBL4863168)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of ERAP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50519953(CHEMBL2140832)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of ERAP1 (unknown origin) using WRCYEKMALK as substrate by Michaelis-Menten analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM661078(US20240101542, Compound 25 | (S)-N-hydroxy-3-(4-me...)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of ERAP1 (unknown origin) using L-AMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50353019(CHEMBL1821981)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of human recombinant ERAP1 expressed in baculovirus infected sf9 cells using L-AMC as substrate incubated for 5 to 10 mins by Michaelis-Me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50635827(CHEMBL5557364)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of ERAP1 (unknown origin) using L-pNA as susbtrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50245355(CHEMBL4070078)
Affinity DataIC50: 7.47E+3nMAssay Description:Inhibition of ERAP1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50078825(phenyl(phenylsulfonyl)amine | N-Phenyl-benzenesulf...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of ERAP1 (unknown origin) using L-pNA as susbtrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
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