Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50021827
TargetSerine/threonine-protein kinase B-raf(Human)
Princess Nourah bint Abdulrahman University

Curated by ChEMBL
LigandPNGBDBM50645270(CHEMBL5566280)
Affinity DataKi:  0.130nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Princess Nourah bint Abdulrahman University

Curated by ChEMBL
LigandPNGBDBM50311470(CHEMBL1079742 | Erlotinib | CP-358774-01 | OSI-774...)
Affinity DataIC50: 60nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Princess Nourah bint Abdulrahman University

Curated by ChEMBL
LigandPNGBDBM50645272(CHEMBL5564483)
Affinity DataIC50: 67nMAssay Description:Inhibition of his6-tagged EGFR (unknown origin) (641 to 1186 residues) expressed in baculovirus Sf9 cells incubated for 1 hr in presence of ATP and M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Princess Nourah bint Abdulrahman University

Curated by ChEMBL
LigandPNGBDBM50645273(CHEMBL5572882)
Affinity DataIC50: 71nMAssay Description:Inhibition of his6-tagged EGFR (unknown origin) (641 to 1186 residues) expressed in baculovirus Sf9 cells incubated for 1 hr in presence of ATP and M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Princess Nourah bint Abdulrahman University

Curated by ChEMBL
LigandPNGBDBM50645274(CHEMBL5589692)
Affinity DataIC50: 78nMAssay Description:Inhibition of his6-tagged EGFR (unknown origin) (641 to 1186 residues) expressed in baculovirus Sf9 cells incubated for 1 hr in presence of ATP and M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Princess Nourah bint Abdulrahman University

Curated by ChEMBL
LigandPNGBDBM50311470(CHEMBL1079742 | Erlotinib | CP-358774-01 | OSI-774...)
Affinity DataIC50: 80nMAssay Description:Inhibition of his6-tagged EGFR (unknown origin) (641 to 1186 residues) expressed in baculovirus Sf9 cells incubated for 1 hr in presence of ATP and M...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Princess Nourah bint Abdulrahman University

Curated by ChEMBL
LigandPNGBDBM50311470(CHEMBL1079742 | Erlotinib | CP-358774-01 | OSI-774...)
Affinity DataIC50: 80nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Princess Nourah bint Abdulrahman University

Curated by ChEMBL
LigandPNGBDBM50645275(CHEMBL5593262)
Affinity DataIC50: 84nMAssay Description:Inhibition of his6-tagged EGFR (unknown origin) (641 to 1186 residues) expressed in baculovirus Sf9 cells incubated for 1 hr in presence of ATP and M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Princess Nourah bint Abdulrahman University

Curated by ChEMBL
LigandPNGBDBM50645271(CHEMBL5565187)
Affinity DataIC50: 96nMAssay Description:Inhibition of his6-tagged EGFR (unknown origin) (641 to 1186 residues) expressed in baculovirus Sf9 cells incubated for 1 hr in presence of ATP and M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Princess Nourah bint Abdulrahman University

Curated by ChEMBL
LigandPNGBDBM50645267(CHEMBL5569987)
Affinity DataIC50: 105nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Princess Nourah bint Abdulrahman University

Curated by ChEMBL
LigandPNGBDBM50645267(CHEMBL5569987)
Affinity DataIC50: 140nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Princess Nourah bint Abdulrahman University

Curated by ChEMBL
LigandPNGBDBM50645268(CHEMBL5572677)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Princess Nourah bint Abdulrahman University

Curated by ChEMBL
LigandPNGBDBM50645269(CHEMBL5575223)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Princess Nourah bint Abdulrahman University

Curated by ChEMBL
LigandPNGBDBM50645268(CHEMBL5572677)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of BRAF V600E mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed