Compile Data Set for Download or QSAR
Report error Found 52 Enz. Inhib. hit(s) with all data for entry = 50021831
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  0.600nMAssay Description:Competitive tight binding inhibition of recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645308(CHEMBL5562941)
Affinity DataKi:  1.20nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645307(CHEMBL5573803)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645305(CHEMBL5590035)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645298(CHEMBL5574204)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645296(CHEMBL5575948)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645296(CHEMBL5575948)
Affinity DataKi:  3.30nMAssay Description:Binding affinity to recombinant human Matriptase using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645299(CHEMBL5569457)
Affinity DataKi:  3.40nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645301(CHEMBL5571372)
Affinity DataKi:  3.70nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645302(CHEMBL5569773)
Affinity DataKi:  3.90nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645307(CHEMBL5573803)
Affinity DataKi:  4.10nMAssay Description:Binding affinity to recombinant human Matriptase using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human TMPRSS6 transfected in HEK293SL cells using Boc-QAR-AMC as substrate measured for 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645297(CHEMBL5592173)
Affinity DataKi:  4.60nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  4.80nMAssay Description:Competitive tight binding inhibition of recombinant human Matriptase using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645298(CHEMBL5574204)
Affinity DataKi:  5nMAssay Description:Binding affinity to recombinant human Matriptase using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645309(CHEMBL5562937)
Affinity DataKi:  5.20nMAssay Description:Competitive tight binding inhibition of recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645299(CHEMBL5569457)
Affinity DataKi:  5.30nMAssay Description:Competitive tight binding inhibition of recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645300(CHEMBL5595012)
Affinity DataKi:  5.60nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645304(CHEMBL5574444)
Affinity DataKi:  7.90nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645306(CHEMBL5566155)
Affinity DataKi:  8.30nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  8.60nMAssay Description:Binding affinity to recombinant human Matriptase using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645305(CHEMBL5590035)
Affinity DataKi:  8.80nMAssay Description:Binding affinity to recombinant human Matriptase using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645302(CHEMBL5569773)
Affinity DataKi:  9.10nMAssay Description:Binding affinity to recombinant human Matriptase using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645308(CHEMBL5562941)
Affinity DataKi:  11nMAssay Description:Binding affinity to recombinant human Matriptase using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645306(CHEMBL5566155)
Affinity DataKi:  12nMAssay Description:Binding affinity to recombinant human Matriptase using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645303(CHEMBL5596033)
Affinity DataKi:  13nMAssay Description:Binding affinity to recombinant human TMPRSS6 using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataIC50: 18nMAssay Description:Inhibition of human Matriptase transfected in HEK293SL cells using Boc-QAR-AMC as substrate measured for 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645299(CHEMBL5569457)
Affinity DataIC50: 22nMAssay Description:Inhibition of human TMPRSS6 transfected in HEK293SL cells using Boc-QAR-AMC as substrate measured for 24 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645300(CHEMBL5595012)
Affinity DataKi:  27nMAssay Description:Binding affinity to recombinant human Matriptase using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645303(CHEMBL5596033)
Affinity DataKi:  34nMAssay Description:Binding affinity to recombinant human Matriptase using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645301(CHEMBL5571372)
Affinity DataKi:  45nMAssay Description:Binding affinity to recombinant human Matriptase using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645297(CHEMBL5592173)
Affinity DataKi:  51nMAssay Description:Binding affinity to recombinant human Matriptase using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProthrombin(Human)TBA
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  53nMAssay Description:Inhibition of recombinant human thrombin using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645304(CHEMBL5574444)
Affinity DataKi:  53nMAssay Description:Binding affinity to recombinant human Matriptase using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645299(CHEMBL5569457)
Affinity DataKi:  99nMAssay Description:Binding affinity to recombinant human Matriptase using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645299(CHEMBL5569457)
Affinity DataKi:  100nMAssay Description:Mixed inhibition of recombinant human Matriptase using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProthrombin(Human)TBA
LigandPNGBDBM50645299(CHEMBL5569457)
Affinity DataKi:  120nMAssay Description:Inhibition of recombinant human thrombin using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor X(Human)TBA
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  323nMAssay Description:Inhibition of FXA (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645309(CHEMBL5562937)
Affinity DataIC50: 332nMAssay Description:Inhibition of human TMPRSS6 transfected in HEK293SL cells using Boc-QAR-AMC as substrate measured for 24 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645299(CHEMBL5569457)
Affinity DataIC50: 352nMAssay Description:Inhibition of human Matriptase transfected in HEK293SL cells using Boc-QAR-AMC as substrate measured for 24 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProthrombin(Human)TBA
LigandPNGBDBM50645309(CHEMBL5562937)
Affinity DataKi:  395nMAssay Description:Inhibition of recombinant human thrombin using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645309(CHEMBL5562937)
Affinity DataKi:  618nMAssay Description:Mixed inhibition of recombinant human Matriptase using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetProthrombin(Human)TBA
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of thrombin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor X(Human)TBA
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi:  2.32E+3nMAssay Description:Inhibition of recombinant human FXA using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50645309(CHEMBL5562937)
Affinity DataIC50: 6.07E+3nMAssay Description:Inhibition of human Matriptase transfected in HEK293SL cells using Boc-QAR-AMC as substrate measured for 24 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetFurin(Human)TBA
LigandPNGBDBM50645309(CHEMBL5562937)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human furin using Boc-RVRR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetFurin(Human)TBA
LigandPNGBDBM50645299(CHEMBL5569457)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human furin using Boc-RVRR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetFurin(Human)TBA
LigandPNGBDBM50236918(CHEMBL4081543)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human furin using Boc-RVRR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetCoagulation factor X(Human)TBA
LigandPNGBDBM50645309(CHEMBL5562937)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of recombinant human FXA using Boc-QAR-AMC as substrate assessed as inhibition constant by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
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