Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50022133
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Shihezi University

Curated by ChEMBL
LigandPNGBDBM50648519(CHEMBL5614132)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of SIRT2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Shihezi University

Curated by ChEMBL
LigandPNGBDBM50648519(CHEMBL5614132)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of SIRT1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50648519(CHEMBL5614132)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human SIRT3 using Fluor de lys as substrate incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50648517(CHEMBL5612303)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human SIRT3 using Fluor de lys as substrate incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50648515(CHEMBL5612571)
Affinity DataIC50: 114nMAssay Description:Inhibition of recombinant human SIRT3 using Fluor de lys as substrate incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50648516(CHEMBL5614219)
Affinity DataIC50: 125nMAssay Description:Inhibition of recombinant human SIRT3 using Fluor de lys as substrate incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50648518(CHEMBL5612107)
Affinity DataIC50: 326nMAssay Description:Inhibition of recombinant human SIRT3 using Fluor de lys as substrate incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Shihezi University

Curated by ChEMBL
LigandPNGBDBM50648517(CHEMBL5612303)
Affinity DataIC50: 387nMAssay Description:Inhibition of N-terminal recombinant his-tagged human SIRT1 expressed in Escherichia coli using Fluor de lys as substrate incubated for 30 mins by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Shihezi University

Curated by ChEMBL
LigandPNGBDBM50648517(CHEMBL5612303)
Affinity DataIC50: 474nMAssay Description:Inhibition of recombinant human SIRT2 using Fluor de lys as substrate incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50648520(CHEMBL2208038)
Affinity DataIC50: 1.43E+5nMAssay Description:Inhibition of wild type C-terminal human SIRT3 (118 to 339 residues) expressed in Escherichia coli strain BL21DE3 Rosetta2 using Fluor de lys as subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)