Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50022135
TargetDNA gyrase subunit B(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50648523(CHEMBL5612596)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of Mycobacterium tuberculosis DNA gyrase using supercoiled pBR322 DNA as substrate incubated for 30 mins by gel based methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50648523(CHEMBL5612596)
Affinity DataIC50: 10nMAssay Description:Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 as substrate measured after 30 mins by SybrGOLD staining based fluorescence microplate r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50127140(4'-Demethylepipodophyllotoxin 9-(4,6-O-(R)-ethylid...)
Affinity DataIC50: 7.10E+4nMAssay Description:Inhibition of human DNA topoisomerase II alpha using supercoiled pNO1 plasmid as substrate incubated for 30 mins by diamond dye staining based fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)