Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 5764
Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM50130275(4-{3-[2-(dimethylamino)ethyl]-1H-indole-1-sulfonyl...)
Affinity DataKi:  0.800nMpH: 7.4Assay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2013
Entry Details Article

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM34141(CHEMBL76237 | MS-245)
Affinity DataKi:  2.10nMAssay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2013
Entry Details Article

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM34150(CHEMBL328816 | 4-(3-methyl-1H-indole-1-sulfonyl)an...)
Affinity DataKi:  12nMpH: 7.4Assay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2013
Entry Details Article

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM34142(2-ethyl-5-methoxy-N,N-dimethyltryptamine | EMDT | ...)
Affinity DataKi:  16nMpH: 7.4Assay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2013
Entry Details Article

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM50085970([2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]dimethy...)
Affinity DataKi:  20nMpH: 7.4Assay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2013
Entry Details Article

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM93162(4-{3-methyl-1H-pyrrolo[3,2-c]pyridine-1-sulfonyl}a...)
Affinity DataKi:  41nMpH: 7.4Assay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2013
Entry Details Article

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM50090528(Ro-04-6790 | 4-Amino-N-(2,6-bis-dimethylamino-pyri...)
Affinity DataKi:  58nMAssay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2013
Entry Details Article

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM93167(2-{1H-pyrrolo[3,2-c]pyridin-3-yl}ethan-1-amine, 9)
Affinity DataKi:  64nMpH: 7.4Assay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2013
Entry Details Article

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM50024210(1H-indole-3-ethanamine | CHEMBL6640 | 2-(3-indolyl...)
Affinity DataKi:  70nMAssay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2013
Entry Details Article

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataKi:  70nMAssay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2013
Entry Details Article

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM30707(3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE | CHEMBL7...)
Affinity DataKi:  70nMpH: 7.4Assay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2013
Entry Details Article

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM93161({2-[1-(benzenesulfonyl)-1H-pyrrolo[3,2-c]pyridin-3...)
Affinity DataKi:  84nMpH: 7.4Assay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2013
Entry Details Article

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM93160(dimethyl(2-{1H-pyrrolo[3,2-c]pyridin-3-yl}ethyl)am...)
Affinity DataKi:  100nMpH: 7.4Assay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2013
Entry Details Article

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM93164(dimethyl(2-{2-phenyl-1H-pyrrolo[3,2-c]pyridin-3-yl...)
Affinity DataKi:  270nMpH: 7.4Assay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2013
Entry Details Article

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM93163(2-{2-phenyl-1H-pyrrolo[3,2-c]pyridin-3-yl}ethan-1-...)
Affinity DataKi:  2.60E+3nMpH: 7.4Assay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2013
Entry Details Article

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM93166((2-{2-ethyl-1H-pyrrolo[3,2-c]pyridin-3-yl}ethyl)di...)
Affinity DataKi:  2.90E+3nMpH: 7.4Assay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2013
Entry Details Article

Target5-hydroxytryptamine receptor 6(Human)
Virginia Commonwealth University

LigandPNGBDBM93165(2-{2-ethyl-1H-pyrrolo[3,2-c]pyridin-3-yl}ethan-1-a...)
Affinity DataKi:  4.90E+3nMpH: 7.4Assay Description:The h5-HT6 radioligand binding assays were performed as previously described. In brief, h5-HT6 cDNA was transiently expressed in HEK-293 cells using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2013
Entry Details Article