Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50021906
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50556493(CHEMBL3561645)
Affinity DataKi:  1nMAssay Description:Displacement of [3H] N-Methylscopolamine from human recombinant M5 receptor expressed in CHO-K1 cell membranes incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50556493(CHEMBL3561645)
Affinity DataIC50: 1.60nMAssay Description:Displacement of [3H] N-Methylscopolamine from human recombinant M5 receptor expressed in CHO-K1 cell membranes incubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50645978(CHEMBL5594532)
Affinity DataIC50: 50nMAssay Description:Displacement of [3H] N-Methylscopolamine from human recombinant M5 receptor expressed in CHO-K1 cell membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50645978(CHEMBL5594532)
Affinity DataKi:  51nMAssay Description:Displacement of [3H] N-Methylscopolamine from human recombinant M5 receptor expressed in CHO-K1 cell membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50645978(CHEMBL5594532)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity to human M2 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50445222(CHEMBL3105228)
Affinity DataIC50: 1.10E+3nMAssay Description:Negative allosteric modulation of human M5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50233360(CHEMBL4062497)
Affinity DataIC50: 1.20E+3nMAssay Description:Negative allosteric modulation of human M5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50645978(CHEMBL5594532)
Affinity DataKi:  2.10E+3nMAssay Description:Binding affinity to human M4 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed