Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50022680
TargetPoly [ADP-ribose] polymerase 1(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592489BDBM50592489(CHEMBL6102162)
Affinity DataIC50: 2.5nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592489BDBM50592489(CHEMBL6102162)
Affinity DataIC50: 6.5nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316226BDBM50316226(MK-4827 | (S)-2-(4-(piperidin-3-yl)phenyl)-2H-inda...)
Affinity DataIC50: 9.20nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Sun Yat-sen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50316226BDBM50316226(MK-4827 | (S)-2-(4-(piperidin-3-yl)phenyl)-2H-inda...)
Affinity DataIC50: 11nMAssay Description:Negative allosteric modulation of rat mGlu3 receptor assessed as calcium mobilization by cell based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2026
Entry Details PubMed