Compile Data Set for Download or QSAR
Report error Found 49 Enz. Inhib. hit(s) with all data for entry = 50021916
TargetGlutamate receptor ionotropic, kainate 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646139(DOMOIC ACID)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H](2S, 4R)-4-MeGlu (SYM-2081) from GluK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646139(DOMOIC ACID)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H](2S, 4R)-4-MeGlu (SYM-2081) from GluK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646139(DOMOIC ACID)
Affinity DataKi:  6nMAssay Description:Displacement of [3H](2S, 4R)-4-MeGlu (SYM-2081) from GluK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor 4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646140(CHEMBL4756304)
Affinity DataIC50: 60nMAssay Description:Displacement of [3H]-AMPA from AMPA in rat synaptic membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646147(CHEMBL5591383)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]-kainic acid from GluR6 (unknown origin) expressed in Sf9 cells membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor 4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646141(CHEMBL351031)
Affinity DataIC50: 130nMAssay Description:Displacement of [3H]-AMPA from AMPA in rat synaptic membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 5(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646128(CHEMBL5594100)
Affinity DataKi:  258nMAssay Description:Displacement of [3H]-kainate from mouse GluK5 expressed in Sf9 cell membrane incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646125(CHEMBL5595349)
Affinity DataKi:  280nMAssay Description:Displacement of [3H]-KA from rat GluK3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 5(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646126(CHEMBL5591694)
Affinity DataKi:  420nMAssay Description:Displacement of [3H]-kainate from mouse GluK5 expressed in Sf9 cell membrane incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 5(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646130(CHEMBL5591808)
Affinity DataKi:  432nMAssay Description:Displacement of [3H]-kainate from mouse GluK5 expressed in Sf9 cell membrane incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor 4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646139(DOMOIC ACID)
Affinity DataIC50: 470nMAssay Description:Displacement of [3H]-AMPA from AMPA in rat synaptic membraneMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 5(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646127(CHEMBL5593461)
Affinity DataKi:  483nMAssay Description:Displacement of [3H]-kainate from mouse GluK5 expressed in Sf9 cell membrane incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 5(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646129(CHEMBL5592920)
Affinity DataKi:  499nMAssay Description:Displacement of [3H]-kainate from mouse GluK5 expressed in Sf9 cell membrane incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 5(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646136(CHEMBL5592030)
Affinity DataKi:  1.02E+3nMAssay Description:Displacement of [3H]-kainate from mouse GluK5 expressed in Sf9 cell membrane incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 5(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646135(CHEMBL5593458)
Affinity DataKi:  1.76E+3nMAssay Description:Displacement of [3H]-kainate from mouse GluK5 expressed in Sf9 cell membrane incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor 4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50002369(Digensaeure | (3S,4R)-3-(carboxymethyl)-4-(prop-1-...)
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of [3H]-AMPA from AMPA in rat synaptic membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 5(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646134(CHEMBL5583740)
Affinity DataKi:  2.15E+3nMAssay Description:Displacement of [3H]-kainate from mouse GluK5 expressed in Sf9 cell membrane incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646125(CHEMBL5595349)
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of [3H]-KA from rat GluK2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 5(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646137(CHEMBL5590355)
Affinity DataKi:  3.25E+3nMAssay Description:Displacement of [3H]-kainate from mouse GluK5 expressed in Sf9 cell membrane incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646125(CHEMBL5595349)
Affinity DataKi:  3.30E+3nMAssay Description:Displacement of [3H]-NF608 from rat GluK1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor 4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646145(CHEMBL5589739)
Affinity DataIC50: 3.60E+3nMAssay Description:Displacement of [3H]-AMPA from AMPA in rat brain membrane preincubated for 15 mins followed by [3H]-AMPA addition and measured after 40 mins by scint...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646128(CHEMBL5594100)
Affinity DataKi:  3.75E+3nMAssay Description:Displacement of [3H]-KA from rat GluK3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 5(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646138(CHEMBL5590299)
Affinity DataKi:  5.35E+3nMAssay Description:Displacement of [3H]-kainate from mouse GluK5 expressed in Sf9 cell membrane incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 5(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646132(CHEMBL5589762)
Affinity DataKi:  5.57E+3nMAssay Description:Displacement of [3H]-kainate from mouse GluK5 expressed in Sf9 cell membrane incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor 4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646142(CHEMBL5594753)
Affinity DataIC50: 5.70E+3nMAssay Description:Displacement of [3H]-AMPA from AMPA in rat brain membrane preincubated for 15 mins followed by [3H]-AMPA addition and measured after 40 mins by scint...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646126(CHEMBL5591694)
Affinity DataKi:  5.90E+3nMAssay Description:Displacement of [3H]-KA from rat GluK3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646127(CHEMBL5593461)
Affinity DataKi:  6.10E+3nMAssay Description:Displacement of [3H]-KA from rat GluK3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646128(CHEMBL5594100)
Affinity DataKi:  7.76E+3nMAssay Description:Displacement of [3H]-KA from rat GluK2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646127(CHEMBL5593461)
Affinity DataKi:  7.79E+3nMAssay Description:Displacement of [3H]-KA from rat GluK2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 5(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646133(CHEMBL5592694)
Affinity DataKi:  7.97E+3nMAssay Description:Displacement of [3H]-kainate from mouse GluK5 expressed in Sf9 cell membrane incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646126(CHEMBL5591694)
Affinity DataKi:  8.66E+3nMAssay Description:Displacement of [3H]-KA from rat GluK2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor 4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646139(DOMOIC ACID)
Affinity DataIC50: 9.00E+3nMAssay Description:Binding affinity to AMPA receptor in rat synaptosomesMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor 4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646125(CHEMBL5595349)
Affinity DataIC50: 9.50E+3nMAssay Description:Displacement of [3H]-AMPA from AMPA in rat cortical synaptosomes incubated for 30 mins by TopCount microplate scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646127(CHEMBL5593461)
Affinity DataKi:  1.08E+4nMAssay Description:Displacement of [3H]-NF608 from rat GluK1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 5(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646131(CHEMBL5590997)
Affinity DataKi:  1.11E+4nMAssay Description:Displacement of [3H]-kainate from mouse GluK5 expressed in Sf9 cell membrane incubated for 2 hrs by scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646128(CHEMBL5594100)
Affinity DataKi:  1.15E+4nMAssay Description:Displacement of [3H]-NF608 from rat GluK1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646126(CHEMBL5591694)
Affinity DataKi:  1.17E+4nMAssay Description:Displacement of [3H]-NF608 from rat GluK1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor 4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50252103(CHEMBL482097 | (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-...)
Affinity DataIC50: 1.20E+4nMAssay Description:Displacement of [3H]-AMPA from AMPA in rat brain membrane preincubated for 15 mins followed by [3H]-AMPA addition and measured after 40 mins by scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor 4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646143(CHEMBL5590005)
Affinity DataIC50: 1.70E+4nMAssay Description:Displacement of [3H]-AMPA from AMPA in rat brain membrane preincubated for 15 mins followed by [3H]-AMPA addition and measured after 40 mins by scint...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646130(CHEMBL5591808)
Affinity DataKi:  1.79E+4nMAssay Description:Displacement of [3H]-KA from rat GluK3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646129(CHEMBL5592920)
Affinity DataKi:  2.11E+4nMAssay Description:Displacement of [3H]-KA from rat GluK3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor 4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646144(CHEMBL5589717)
Affinity DataIC50: 3.20E+4nMAssay Description:Displacement of [3H]-AMPA from AMPA in rat brain membrane preincubated for 15 mins followed by [3H]-AMPA addition and measured after 40 mins by scint...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646129(CHEMBL5592920)
Affinity DataKi:  3.60E+4nMAssay Description:Displacement of [3H]-KA from rat GluK2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646130(CHEMBL5591808)
Affinity DataKi:  7.00E+4nMAssay Description:Displacement of [3H]-KA from rat GluK2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 3(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646124(CHEMBL5595084)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-KA from rat GluK3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor 4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646124(CHEMBL5595084)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]-AMPA from AMPA in rat cortical synaptosomes incubated for 30 mins by TopCount microplate scintillation counting methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 1(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646124(CHEMBL5595084)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-NF608 from rat GluK1More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor 4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646146(CHEMBL5593727)
Affinity DataIC50: 1.00E+5nMAssay Description:Displacement of [3H]-AMPA from AMPA in rat brain membrane preincubated for 15 mins followed by [3H]-AMPA addition and measured after 40 mins by scint...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetGlutamate receptor ionotropic, kainate 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50646124(CHEMBL5595084)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-KA from rat GluK2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed