Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50021991
LigandPNGBDBM50646842(CHEMBL5593159)
Affinity DataKd:  0.540nMAssay Description:Binding affinity to human PP5 extracted from Escherichia coli BL21 using immobilized CDC37 as substrate assessed as increase in PP5 binding to substr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646842(CHEMBL5593159)
Affinity DataKd:  811nMAssay Description:Binding affinity to His-tagged human PP5 phosphatase domain extracted from Escherichia coli BL21 assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646842(CHEMBL5593159)
Affinity DataKd:  1.14E+3nMAssay Description:Binding affinity to full length His-tagged human PP5 extracted from Escherichia coli BL21 assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646843(CHEMBL5592027)
Affinity DataKd:  1.44E+4nMAssay Description:Competitive binding affinity to His-tagged human PP5 TPR domain extracted from Escherichia coli BL21 assessed as dissociation constant preincubated w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646843(CHEMBL5592027)
Affinity DataKd:  1.66E+4nMAssay Description:Binding affinity to His-tagged human PP5 TPR domain extracted from Escherichia coli BL21 assessed as dissociation constant by biolayer interferometri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646844(Lb-100 | LB 100)
Affinity DataIC50: 2.11E+4nMAssay Description:Inhibition of DDO-3733 preincubated human PP5 phosphatase domain extracted from Escherichia coli BL21 using pNPP as substrate incubated for 30 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646844(Lb-100 | LB 100)
Affinity DataIC50: 2.21E+4nMAssay Description:Inhibition of human PP5 phosphatase domain extracted from Escherichia coli BL21 using pNPP as substrate incubated for 30 mins by spectrophotometric a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646842(CHEMBL5593159)
Affinity DataKd:  3.72E+4nMAssay Description:Binding affinity to PP5 K430A mutant (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50646842(CHEMBL5593159)
Affinity DataEC50:  5.28E+4nMAssay Description:Activation of His-tagged human PP5 extracted from Escherichia coli BL21 using pNPP as substrate assessed as increase in phosphatase activity incubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed