Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50022086
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataKd:  16nMAssay Description:Displacement of dansylamide from human recombinant CA II expressed in Escherichia coli BL21 DE3 assessed as dissociation constant by fluorescence mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKd:  20nMAssay Description:Displacement of dansylamide from human recombinant CA II expressed in Escherichia coli BL21 DE3 assessed as dissociation constant by fluorescence mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKd:  46nMAssay Description:Binding affinity to human recombinant CA II expressed in Escherichia coli assessed as dissociation constant by fluorescent thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50013792(CHEBI:6822 | Neptazane | METHAZOLAMIDE)
Affinity DataKd:  55nMAssay Description:Displacement of dansylamide from human recombinant CA II expressed in Escherichia coli BL21 DE3 assessed as dissociation constant by fluorescence mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50647947(Indapamide | Indapamida | Arifon | Bajaten | Damid...)
Affinity DataKd:  130nMAssay Description:Binding affinity to human recombinant CA II assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM13076(JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...)
Affinity DataKi:  290nMAssay Description:Binding affinity to human recombinant CA II assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM25902(4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbe...)
Affinity DataKd:  630nMAssay Description:Binding affinity to human recombinant CA II assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50647947(Indapamide | Indapamida | Arifon | Bajaten | Damid...)
Affinity DataKd:  1.42E+3nMAssay Description:Displacement of dansylamide from human recombinant CA II expressed in Escherichia coli BL21 DE3 assessed as dissociation constant by fluorescence mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50238678(CHEBI:3013 | Aprinox | Bendrofluazide | Bendroflum...)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to human recombinant CA II assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50647948(Trichlormethiazide | Triclormetiazida | Trichlorom...)
Affinity DataKd:  1.70E+3nMAssay Description:Binding affinity to human recombinant CA II assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM25899(7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...)
Affinity DataKi:  2.00E+3nMAssay Description:Binding affinity to human recombinant CA II assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50647948(Trichlormethiazide | Triclormetiazida | Trichlorom...)
Affinity DataKd:  2.60E+3nMAssay Description:Displacement of dansylamide from human recombinant CA II expressed in Escherichia coli BL21 DE3 assessed as dissociation constant by fluorescence mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM13076(JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...)
Affinity DataKd:  2.60E+3nMAssay Description:Binding affinity to human recombinant CA II assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM25899(7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...)
Affinity DataKd:  2.80E+3nMAssay Description:Binding affinity to human recombinant CA II assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM25902(4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbe...)
Affinity DataKd:  3.14E+3nMAssay Description:Displacement of dansylamide from human recombinant CA II expressed in Escherichia coli BL21 DE3 assessed as dissociation constant by fluorescence mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM25903(Fordiuran | Burinex | cid_2471 | 3-(butylamino)-4-...)
Affinity DataKi:  6.98E+3nMAssay Description:Binding affinity to human recombinant CA II assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM13076(JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...)
Affinity DataKd:  7.19E+3nMAssay Description:Displacement of dansylamide from human recombinant CA II expressed in Escherichia coli BL21 DE3 assessed as dissociation constant by fluorescence mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 3(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50647947(Indapamide | Indapamida | Arifon | Bajaten | Damid...)
Affinity DataKd:  1.10E+4nMAssay Description:Binding affinity to human recombinant CA III assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 3(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKd:  4.00E+4nMAssay Description:Binding affinity to human recombinant CA III expressed in Escherichia coli assessed as dissociation constant by fluorescent thermal shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 3(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM25899(7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...)
Affinity DataKd: >2.00E+5nMAssay Description:Binding affinity to human recombinant CA III assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 3(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50647948(Trichlormethiazide | Triclormetiazida | Trichlorom...)
Affinity DataKd: >2.00E+5nMAssay Description:Binding affinity to human recombinant CA III assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 3(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM25902(4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbe...)
Affinity DataKd: >2.00E+5nMAssay Description:Binding affinity to human recombinant CA III assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 3(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50238678(CHEBI:3013 | Aprinox | Bendrofluazide | Bendroflum...)
Affinity DataKd: >2.00E+5nMAssay Description:Binding affinity to human recombinant CA III assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 3(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM13076(JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...)
Affinity DataKd:  2.00E+5nMAssay Description:Binding affinity to human recombinant CA III assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 3(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM25899(7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4...)
Affinity DataKi:  6.10E+5nMAssay Description:Binding affinity to human recombinant CA III assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 3(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM13076(JFD00715 | cid_3639 | 6-chloro-1,1-dioxo-3,4-dihyd...)
Affinity DataKi:  7.90E+5nMAssay Description:Binding affinity to human recombinant CA III assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetCarbonic anhydrase 3(Human)
Griffith University

Curated by ChEMBL
LigandPNGBDBM25903(Fordiuran | Burinex | cid_2471 | 3-(butylamino)-4-...)
Affinity DataKi:  3.40E+6nMAssay Description:Binding affinity to human recombinant CA III assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed