Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50022212
LigandPNGBDBM50649516(CHEMBL5619806)
Affinity DataIC50: 0.580nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649516(CHEMBL5619806)
Affinity DataIC50: 0.630nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM736420(US20250134882, Example 4)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM736420(US20250134882, Example 4)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of full-length human recombinant PTPN2 incubated for 20 mins by mobile shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM736420(US20250134882, Example 4)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human PTPN2 extracted from Escherichia coli BL21 (DE3) by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50649520(CHEMBL5618445 | US20250257059, Example 110)
Affinity DataIC50: 2nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM736420(US20250134882, Example 4)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649514(CHEMBL5619195)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649514(CHEMBL5619195)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649514(CHEMBL5619195)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human PTPN2 extracted from Escherichia coli BL21 (DE3) by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649514(CHEMBL5619195)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of full-length human recombinant PTPN2 incubated for 20 mins by mobile shift assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50219566(5-(3-(1-(benzylsulfonyl)piperidin-4-ylamino)phenyl...)
Affinity DataKi:  4nMAssay Description:Binding affinity to PTP1B (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50239833((3-bromo-7-cyanonaphthalen-2-yl)difluoromethylphos...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50219566(5-(3-(1-(benzylsulfonyl)piperidin-4-ylamino)phenyl...)
Affinity DataKi:  5nMAssay Description:Binding affinity to PTPN2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649521(CHEMBL5619034)
Affinity DataIC50: 5nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50239833((3-bromo-7-cyanonaphthalen-2-yl)difluoromethylphos...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649518(CHEMBL5618838)
Affinity DataIC50: 10nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649517(CHEMBL5618850)
Affinity DataIC50: 10nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649517(CHEMBL5618850)
Affinity DataIC50: 10nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649522(CHEMBL5618189)
Affinity DataIC50: 10nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649518(CHEMBL5618838)
Affinity DataIC50: 10nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM736608(US20250136564, Example 2)
Affinity DataIC50: 13nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50308852((S)-2-(N-(4-(2-acetamido-3-(4-(3-hydroxy-2-(methox...)
Affinity DataIC50: 18nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM736419(Synthesis of 5-((1S,3R,4S)-5-fluoro-7-hydroxy-3-(i...)
Affinity DataIC50: 27nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649519(CHEMBL5619752)
Affinity DataIC50: 42nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50308852((S)-2-(N-(4-(2-acetamido-3-(4-(3-hydroxy-2-(methox...)
Affinity DataIC50: 65nMAssay Description:Inhibition of PTPN2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
LigandPNGBDBM50649515(CHEMBL5619222)
Affinity DataIC50: 120nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed